diff --git a/Mk/Uses/python.mk b/Mk/Uses/python.mk
--- a/Mk/Uses/python.mk
+++ b/Mk/Uses/python.mk
@@ -153,7 +153,7 @@
 #			  default: ${PYTHONBASE}/bin/${PYTHON_VERSION}
 #
 # PEP517_BUILD_CMD	- Command sequence for a PEP-517 build frontend that builds a wheel.
-#			  default: ${PYTHON_CMD} -m build --no-isolation --wheel ${PEP517_BUILD_CONFIG_SETTING}
+#			  default: ${PYTHON_CMD} -m build --no-isolation --wheel --outdir ${WRKDIR}/whl ${PEP517_BUILD_CONFIG_SETTING}
 #
 # PEP517_BUILD_DEPEND	- Port needed to execute ${PEP517_BUILD_CMD}.
 #			  default: ${PYTHON_PKGNAMEPREFIX}build>=0:devel/py-build@${PY_FLAVOR}
@@ -163,7 +163,7 @@
 #			  default: <empty>
 #
 # PEP517_INSTALL_CMD	- Command sequence for a PEP-517 install frontend that installs a wheel.
-#			  default: ${PYTHON_CMD} -m installer --destdir ${STAGEDIR} --prefix ${PREFIX} ${BUILD_WRKSRC}/dist/${PORTNAME:C|[-_]+|_|g}-${DISTVERSION}*.whl
+#			  default: ${PYTHON_CMD} -m installer --destdir ${STAGEDIR} --prefix ${PREFIX} ${WRKDIR}/whl/${PORTNAME:C|[-_]+|_|g}-${DISTVERSION}*.whl
 #
 # PEP517_INSTALL_DEPEND	- Port needed to execute ${PEP517_INSTALL_CMD}.
 #			  default: ${PYTHON_PKGNAMEPREFIX}installer>=0:devel/py-installer@${PY_FLAVOR}
@@ -188,6 +188,14 @@
 #			- Pass this command to distutils on build stage.
 #			  default: build
 #
+# PYDISTUTILS_BUILD_WHEEL
+#			- Define to build wheel with distutils on build wheel stage.
+#			  default: <not defined>
+#
+# PYDISTUTILS_BUILD_WHEEL_TARGET
+#			- Pass this command to distutils on build wheel stage.
+#			  default: bdist_wheel
+#
 # PYDISTUTILS_INSTALL_TARGET
 #			- Pass this command to distutils on install stage.
 #			  default: install
@@ -200,6 +208,10 @@
 #			- Arguments to build with distutils.
 #			  default: <empty>
 #
+# PYDISTUTILS_BUILDWHEELARGS
+#			- Arguments to build wheel with distutils.
+#			  default: --dist-dir ${WRKDIR}/whl
+#
 # PYDISTUTILS_INSTALLARGS
 #			- Arguments to install with distutils.
 #			  default: -c -O1 --prefix=${PREFIX} --single-version-externally-managed --root=${STAGEDIR}
@@ -709,12 +721,16 @@
 .  if defined(_PYTHON_FEATURE_DISTUTILS) && \
 	${_CURRENTPORT} != ${PYTHON_PKGNAMEPREFIX}setuptools && \
 	${_CURRENTPORT} != ${PYTHON_PKGNAMEPREFIX}setuptools58 && \
-	${_CURRENTPORT} != ${PYTHON_PKGNAMEPREFIX}setuptools44
+	${_CURRENTPORT} != ${PYTHON_PKGNAMEPREFIX}setuptools44 && \
+	${_CURRENTPORT} != ${PYTHON_PKGNAMEPREFIX}wheel
 .    if ${PYTHON_VER} == 2.7
 BUILD_DEPENDS+=		${PYTHON_PKGNAMEPREFIX}setuptools44>0:devel/py-setuptools44@${PY_FLAVOR}
 RUN_DEPENDS+=		${PYTHON_PKGNAMEPREFIX}setuptools44>0:devel/py-setuptools44@${PY_FLAVOR}
 .    else
 BUILD_DEPENDS+=		${PYTHON_PKGNAMEPREFIX}setuptools>=63.1.0:devel/py-setuptools@${PY_FLAVOR}
+.      if defined(PYDISTUTILS_BUILD_WHEEL)
+BUILD_DEPENDS+=		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
+.      endif
 .    endif
 .  endif
 
@@ -741,6 +757,7 @@
 	exec(compile(open(__file__, 'rb').read().replace(b'\\r\\n', b'\\n'), __file__, 'exec'))"
 PYDISTUTILS_CONFIGUREARGS?=	# empty
 PYDISTUTILS_BUILDARGS?=		# empty
+PYDISTUTILS_BUILDWHEELARGS?=	--dist-dir ${WRKDIR}/whl
 PYDISTUTILS_INSTALLARGS?=	-c -O1 --prefix=${PREFIX}
 .  if defined(_PYTHON_FEATURE_DISTUTILS)
 .    if !defined(PYDISTUTILS_INSTALLNOSINGLE)
@@ -757,9 +774,9 @@
 PYDISTUTILS_EGGINFODIR?=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 # PEP-517 support
-PEP517_BUILD_CMD?=	${PYTHON_CMD} -m build --no-isolation --wheel ${PEP517_BUILD_CONFIG_SETTING}
+PEP517_BUILD_CMD?=	${PYTHON_CMD} -m build --no-isolation --wheel --outdir ${WRKDIR}/whl ${PEP517_BUILD_CONFIG_SETTING}
 PEP517_BUILD_DEPEND?=	${PYTHON_PKGNAMEPREFIX}build>=0:devel/py-build@${PY_FLAVOR}
-PEP517_INSTALL_CMD?=	${PYTHON_CMD} -m installer --destdir ${STAGEDIR} --prefix ${PREFIX} ${BUILD_WRKSRC}/dist/${PORTNAME:C|[-_]+|_|g}-${DISTVERSION}*.whl
+PEP517_INSTALL_CMD?=	${PYTHON_CMD} -m installer --destdir ${STAGEDIR} --prefix ${PREFIX} ${WRKDIR}/whl/${PORTNAME:C|[-_]+|_|g}-${DISTVERSION}*.whl
 PEP517_INSTALL_DEPEND?=	${PYTHON_PKGNAMEPREFIX}installer>=0:devel/py-installer@${PY_FLAVOR}
 
 # nose support
@@ -944,6 +961,7 @@
 # py-distutils support
 PYDISTUTILS_CONFIGURE_TARGET?=	config
 PYDISTUTILS_BUILD_TARGET?=	build
+PYDISTUTILS_BUILD_WHEEL_TARGET?=	bdist_wheel
 PYDISTUTILS_INSTALL_TARGET?=	install
 
 .  if defined(_PYTHON_FEATURE_DISTUTILS)
@@ -958,6 +976,9 @@
 .    if !target(do-build)
 do-build:
 	@(cd ${BUILD_WRKSRC}; ${SETENVI} ${WRK_ENV} ${MAKE_ENV} ${PYTHON_CMD} ${PYDISTUTILS_SETUP} ${PYDISTUTILS_BUILD_TARGET} ${PYDISTUTILS_BUILDARGS})
+.      if defined(PYDISTUTILS_BUILD_WHEEL)
+	@(cd ${BUILD_WRKSRC}; ${SETENVI} ${WRK_ENV} ${MAKE_ENV} ${PYTHON_CMD} ${PYDISTUTILS_SETUP} ${PYDISTUTILS_BUILD_WHEEL_TARGET} ${PYDISTUTILS_BUILDWHEELARGS})
+.      endif
 .    endif
 
 .    if !target(do-install)