diff --git a/devel/py-preshed/Makefile b/devel/py-preshed/Makefile
index de3a780f3b85..d84968a41a0d 100644
--- a/devel/py-preshed/Makefile
+++ b/devel/py-preshed/Makefile
@@ -1,25 +1,28 @@
 PORTNAME=	preshed
-PORTVERSION=	3.0.8
+DISTVERSION=	4.0.0
 CATEGORIES=	devel python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Cython hash table
 WWW=		https://github.com/explosion/preshed
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-PY_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cymem>=2.0.2,<2.1.0:devel/py-cymem@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}murmurhash>=0.28.0,<1.1.0:devel/py-murmurhash@${PY_FLAVOR}
-BUILD_DEPENDS=	${PY_DEPENDS}
+PY_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cymem>=2.0.2<2.1.0:devel/py-cymem@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}murmurhash>=0.28.0<1.1.0:devel/py-murmurhash@${PY_FLAVOR}
+BUILD_DEPENDS=	${PY_DEPENDS} \
+		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
 RUN_DEPENDS=	${PY_DEPENDS}
 
 USES=		python:3.6+
-USE_PYTHON=	cython distutils autoplist
+USE_PYTHON=	pep517 cython autoplist pytest # tests fail, see https://github.com/explosion/preshed/issues/45
+
+TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 post-install:
 	@${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/preshed/*.so
 
 .include <bsd.port.mk>
diff --git a/devel/py-preshed/distinfo b/devel/py-preshed/distinfo
index 17802319baa3..2ef3f97da6e8 100644
--- a/devel/py-preshed/distinfo
+++ b/devel/py-preshed/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1679240186
-SHA256 (preshed-3.0.8.tar.gz) = 6c74c70078809bfddda17be96483c41d06d717934b07cab7921011d81758b357
-SIZE (preshed-3.0.8.tar.gz) = 14501
+TIMESTAMP = 1682874780
+SHA256 (preshed-4.0.0.tar.gz) = 5e2b0b2a07dd1a8deeaad6612019845c602ee24907f6936eaaf17aabd56e544c
+SIZE (preshed-4.0.0.tar.gz) = 16273