diff --git a/biology/bamtools/Makefile b/biology/bamtools/Makefile
index 8ba4a4d667ec..775c1f88cb59 100644
--- a/biology/bamtools/Makefile
+++ b/biology/bamtools/Makefile
@@ -1,22 +1,23 @@
 PORTNAME=	bamtools
 DISTVERSIONPREFIX=	v
-DISTVERSION=	2.5.2
-PORTREVISION=	2
+DISTVERSION=	2.5.3
 CATEGORIES=	biology
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	API and toolkit for handling BAM files
 WWW=		https://github.com/pezmaster31/bamtools
 
 LICENSE=	MIT
 
 LIB_DEPENDS+=	libjsoncpp.so:devel/jsoncpp
 
 USES=		cmake
 USE_LDCONFIG=	yes
 USE_GITHUB=	yes
 GH_ACCOUNT=	pezmaster31
 
 CMAKE_ON+=	BUILD_SHARED_LIBS
 
+PLIST_SUB=	PORTVERSION=${PORTVERSION}
+
 .include <bsd.port.mk>
diff --git a/biology/bamtools/distinfo b/biology/bamtools/distinfo
index e36197452212..dd64a579b51b 100644
--- a/biology/bamtools/distinfo
+++ b/biology/bamtools/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1625529459
-SHA256 (pezmaster31-bamtools-v2.5.2_GH0.tar.gz) = 4d8b84bd07b673d0ed41031348f10ca98dd6fa6a4460f9b9668d6f1d4084dfc8
-SIZE (pezmaster31-bamtools-v2.5.2_GH0.tar.gz) = 245729
+TIMESTAMP = 1747676701
+SHA256 (pezmaster31-bamtools-v2.5.3_GH0.tar.gz) = 7d4e59bac7c03bde488fe43e533692f78b5325a097328785ec31373ffac08344
+SIZE (pezmaster31-bamtools-v2.5.3_GH0.tar.gz) = 245648
diff --git a/biology/bamtools/pkg-descr b/biology/bamtools/pkg-descr
index 632f635d85bd..e5116b7fbba8 100644
--- a/biology/bamtools/pkg-descr
+++ b/biology/bamtools/pkg-descr
@@ -1,7 +1,6 @@
 BamTools provides both a programmer's API and an end-user's toolkit for
 handling BAM files.
-
 BAM is the binary alternative to the sequence alignment/map (SAM) format used
 for storing genetic sequence data. It uses BGZF block compression implemented
 on top of the standard gzip file format to provide good compression while
 allowing efficient random access for indexed queries.
diff --git a/biology/bamtools/pkg-plist b/biology/bamtools/pkg-plist
index a976799fd806..df5a98027cbe 100644
--- a/biology/bamtools/pkg-plist
+++ b/biology/bamtools/pkg-plist
@@ -1,25 +1,25 @@
 bin/bamtools
 include/bamtools/api/BamAlgorithms.h
 include/bamtools/api/BamAlignment.h
 include/bamtools/api/BamAux.h
 include/bamtools/api/BamConstants.h
 include/bamtools/api/BamIndex.h
 include/bamtools/api/BamMultiReader.h
 include/bamtools/api/BamReader.h
 include/bamtools/api/BamWriter.h
 include/bamtools/api/IBamIODevice.h
 include/bamtools/api/SamConstants.h
 include/bamtools/api/SamHeader.h
 include/bamtools/api/SamProgram.h
 include/bamtools/api/SamProgramChain.h
 include/bamtools/api/SamReadGroup.h
 include/bamtools/api/SamReadGroupDictionary.h
 include/bamtools/api/SamSequence.h
 include/bamtools/api/SamSequenceDictionary.h
 include/bamtools/api/algorithms/Sort.h
 include/bamtools/api/api_global.h
 include/bamtools/api/bamtools_api_export.h
 include/bamtools/shared/bamtools_global.h
 lib/libbamtools.so
-lib/libbamtools.so.2.5.2
+lib/libbamtools.so.%%PORTVERSION%%
 libdata/pkgconfig/bamtools-1.pc