diff --git a/misc/py-anthropic/Makefile b/misc/py-anthropic/Makefile
index 1d764df39a67..6beff670faea 100644
--- a/misc/py-anthropic/Makefile
+++ b/misc/py-anthropic/Makefile
@@ -1,31 +1,31 @@
 PORTNAME=	anthropic
-DISTVERSION=	0.64.0
+DISTVERSION=	0.100.0
 CATEGORIES=	misc python # machine-learning
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
-MAINTAINER=	ports@FreeBSD.org
+MAINTAINER=	olivier@FreeBSD.org
 COMMENT=	Convenient access to the Anthropic REST API via python
 WWW=		https://github.com/anthropics/anthropic-sdk-python
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}hatch-fancy-pypi-readme>=0:devel/py-hatch-fancy-pypi-readme@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hatchling>=0:devel/py-hatchling@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}anyio>=3.5.0:devel/py-anyio@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}distro>=1.7.0:sysutils/py-distro@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}docstring_parser>=0.15:textproc/py-docstring_parser@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}httpx>=0.25.0:www/py-httpx@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jiter>=0.4.0:textproc/py-jiter@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pydantic2>=1.9.0:devel/py-pydantic2@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}sniffio>=0:devel/py-sniffio@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}tokenizers>=0:textproc/py-tokenizers@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}typing-extensions>=4.10:devel/py-typing-extensions@${PY_FLAVOR}
+		${PYTHON_PKGNAMEPREFIX}typing-extensions>=4.14:devel/py-typing-extensions@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	pep517 autoplist
 
 NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/misc/py-anthropic/distinfo b/misc/py-anthropic/distinfo
index bfad285e1a16..9dcf85eb37dd 100644
--- a/misc/py-anthropic/distinfo
+++ b/misc/py-anthropic/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1756024233
-SHA256 (anthropic-0.64.0.tar.gz) = 3d496c91a63dff64f451b3e8e4b238a9640bf87b0c11d0b74ddc372ba5a3fe58
-SIZE (anthropic-0.64.0.tar.gz) = 427893
+TIMESTAMP = 1778175599
+SHA256 (anthropic-0.100.0.tar.gz) = 650dee9e023afb16395939ee4104bbc21f966b380210119fb91122c12099c79a
+SIZE (anthropic-0.100.0.tar.gz) = 758255
diff --git a/misc/py-anthropic/files/patch-pyproject.toml b/misc/py-anthropic/files/patch-pyproject.toml
index b14aec397d19..cab5675e6923 100644
--- a/misc/py-anthropic/files/patch-pyproject.toml
+++ b/misc/py-anthropic/files/patch-pyproject.toml
@@ -1,11 +1,11 @@
---- pyproject.toml.orig	2025-08-24 08:31:41 UTC
+--- pyproject.toml.orig	2020-02-02 00:00:00 UTC
 +++ pyproject.toml
-@@ -65,7 +65,7 @@ dev-dependencies = [
+@@ -95,7 +95,7 @@ pydantic-v2 = [
  ]
  
  [build-system]
 -requires = ["hatchling==1.26.3", "hatch-fancy-pypi-readme"]
 +requires = ["hatchling>=1.26.3", "hatch-fancy-pypi-readme"]
  build-backend = "hatchling.build"
  
  [tool.hatch.build]