diff --git a/science/py-nibabel/Makefile b/science/py-nibabel/Makefile
index 9c8c273ebcef..53095e67cfeb 100644
--- a/science/py-nibabel/Makefile
+++ b/science/py-nibabel/Makefile
@@ -1,36 +1,41 @@
 PORTNAME=	nibabel
-DISTVERSION=	5.2.1
+DISTVERSION=	5.3.0
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Read/write some common neuroimaging file formats
 WWW=		https://nipy.org/nibabel/
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}hatch-vcs>0:devel/py-hatch-vcs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hatchling>0:devel/py-hatchling@${PY_FLAVOR}
 RUN_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}packaging>=17:devel/py-packaging@${PY_FLAVOR}
+py311_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}importlib-resources>=1.1.0:devel/py-importlib-resources@${PY_FLAVOR} \
+			${PYTHON_PKGNAMEPREFIX}typing-extensions>=4.6:devel/py-typing-extensions@${PY_FLAVOR}
+py312_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}typing-extensions>=4.6:devel/py-typing-extensions@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pytest-cov>0:devel/py-pytest-cov@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-doctestplus>0:devel/py-pytest-doctestplus@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-httpserver>0:devel/py-pytest-httpserver@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-xdist>0:devel/py-pytest-xdist@${PY_FLAVOR}
 TEST_DEPENDS+=	${PYTHON_PKGNAMEPREFIX}pydicom>0:science/py-pydicom@${PY_FLAVOR}
 
 USES=		python:3.9+
-USE_PYTHON=	pep517 concurrent autoplist pytest # 270 tests fail, see https://github.com/nipy/nibabel/issues/1317
+USE_PYTHON=	pep517 concurrent autoplist pytest # 1 test fails, see https://github.com/nipy/nibabel/issues/1375
 
 NO_ARCH=	yes
 
 TEST_ENV=	${MAKE_ENV} PATH=${STAGEDIR}${PREFIX}/bin
 
 post-install:
 	@${REINPLACE_CMD} -i '' -e 's|#!python|#!${PYTHON_CMD}|' \
 		${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/nibabel/cmdline/diff.py  \
 		${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/nibabel/cmdline/ls.py 
 
+# tests: 1 failed, 5175 passed, 267 skipped, 35 xfailed, 5 xpassed, 508 warnings, 1 error in 296.51s (0:04:56)
+
 .include <bsd.port.mk>
diff --git a/science/py-nibabel/distinfo b/science/py-nibabel/distinfo
index a084cf7c824c..58e7efc538b0 100644
--- a/science/py-nibabel/distinfo
+++ b/science/py-nibabel/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1713047802
-SHA256 (nibabel-5.2.1.tar.gz) = b6c80b2e728e4bc2b65f1142d9b8d2287a9102a8bf8477e115ef0d8334559975
-SIZE (nibabel-5.2.1.tar.gz) = 4503320
+TIMESTAMP = 1728519444
+SHA256 (nibabel-5.3.0.tar.gz) = 6162184e0249b317bca42b2f43c02734a51e82ebd4ca9ee6200e25648493438e
+SIZE (nibabel-5.3.0.tar.gz) = 4504200