diff --git a/science/py-pyscf/Makefile b/science/py-pyscf/Makefile
index eeeaf1421b7c..15b617347fe5 100644
--- a/science/py-pyscf/Makefile
+++ b/science/py-pyscf/Makefile
@@ -1,44 +1,43 @@
 PORTNAME=	pyscf
 DISTVERSIONPREFIX=	v
-DISTVERSION=	2.1.0
-PORTREVISION=	2
+DISTVERSION=	2.1.1
 CATEGORIES=	science python
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Python module for quantum chemistry
 WWW=		https://pyscf.org/
 
 LICENSE=	BSD2CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 PY_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}scipy>0:science/py-scipy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}h5py>=2.7:science/py-h5py@${PY_FLAVOR}
 BUILD_DEPENDS=	${PY_DEPENDS} \
 		cmake:devel/cmake-core \
 		gmake:devel/gmake
 LIB_DEPENDS=	libcint.so:science/libcint \
 		libxc.so:science/libxc \
 		libxcfun.so:science/xcfun
 RUN_DEPENDS=	${PY_DEPENDS}
 
 USES=		fortran blaslapack:openblas compiler:c++11-lang python
-USE_PYTHON=	distutils autoplist pytest
+USE_PYTHON=	distutils autoplist pytest # 3818 warnings, 57 errors in tests, see https://github.com/pyscf/pyscf/issues/1536
 USE_GITHUB=	yes
 
 POST_PLIST=	fix-plist
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 post-install:
 	@${STRIP_CMD} ${STAGEDIR}${PYTHON_SITELIBDIR}/pyscf/lib/lib*.so
 
 fix-plist:
 	@${REINPLACE_CMD} -e 's|.*pyscf_lib_placeholder.so$$||' ${TMPPLIST}
 
 post-test:
 	@${ECHO} "==> simple test ..."
 	@${SETENV} ${TEST_ENV} ${PYTHON_CMD} ${FILESDIR}/test.py
 
 .include <bsd.port.mk>
diff --git a/science/py-pyscf/distinfo b/science/py-pyscf/distinfo
index 567ada652865..5bff06f258b2 100644
--- a/science/py-pyscf/distinfo
+++ b/science/py-pyscf/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1662267235
-SHA256 (pyscf-pyscf-v2.1.0_GH0.tar.gz) = 820da1564047de3097ec2f964a4c2168535a8048c084f211b8db1feb0c1665af
-SIZE (pyscf-pyscf-v2.1.0_GH0.tar.gz) = 10896918
+TIMESTAMP = 1670658450
+SHA256 (pyscf-pyscf-v2.1.1_GH0.tar.gz) = 814240aa73f57ba96aee8264e3914c09f96ebdce1e42784da4b5e9a474ecb280
+SIZE (pyscf-pyscf-v2.1.1_GH0.tar.gz) = 10896271
diff --git a/science/py-pyscf/files/patch-pyscf_lib_gto_ft__ao.c b/science/py-pyscf/files/patch-pyscf_lib_gto_ft__ao.c
new file mode 100644
index 000000000000..1d2f9c022ac4
--- /dev/null
+++ b/science/py-pyscf/files/patch-pyscf_lib_gto_ft__ao.c
@@ -0,0 +1,13 @@
+- wprkaropund for compilation failure on armv7
+- #include <stdint.h> for int8_t, see https://github.com/pyscf/pyscf/issues/1535
+
+--- pyscf/lib/gto/ft_ao.c.orig	2022-12-10 07:40:03 UTC
++++ pyscf/lib/gto/ft_ao.c
+@@ -44,6 +44,7 @@
+ 
+ #include <stdlib.h>
+ #include <stdio.h>
++#include <stdint.h>
+ #include <math.h>
+ #include <assert.h>
+ #include <complex.h>