diff --git a/science/thermofun/Makefile b/science/thermofun/Makefile
index 6e9e9d4e39f0..652e289dbc1c 100644
--- a/science/thermofun/Makefile
+++ b/science/thermofun/Makefile
@@ -1,48 +1,48 @@
 PORTNAME=	thermofun
 DISTVERSIONPREFIX=	v
-DISTVERSION=	0.5.0
+DISTVERSION=	0.5.1
 CATEGORIES=	science # chemistry
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Code for calculating thermodynamic properties of materials
 WWW=		https://github.com/thermohub/thermofun/
 
 LICENSE=	LGPL3
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	nlohmann-json>0:devel/nlohmann-json \
 		spdlog>0:devel/spdlog
 LIB_DEPENDS=	libChemicalFun.so:science/chemicalfun
 
 USES=		cmake
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	thermohub
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 CXXFLAGS+=	-DSPDLOG_FMT_EXTERNAL # see https://bugs.freebsd.org/bugzilla/show_bug.cgi?id=258073#c3
 
 TEST_WRKSRC=	${WRKSRC}
 
 OPTIONS_DEFINE=		PYTHON
 OPTIONS_DEFAULT=	PYTHON
 OPTIONS_SUB=		yes
 
 PYTHON_BUILD_DEPENDS=	pybind11>0:devel/pybind11 \
 			${PY_SETUPTOOLS} \
 			${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR} \
 			${PYTHON_PKGNAMEPREFIX}pip>0:devel/py-pip@${PY_FLAVOR}
 PYTHON_USES=		python
 PYTHON_USE=		PYTHON=pytest
 PYTHON_CMAKE_BOOL=	TFUN_BUILD_PYTHON
 PYTHON_CMAKE_ON=	-DFREEBSD_STAGEDIR=${STAGEDIR} -DFREEBSD_PREFIX=${PREFIX}
 
 post-install-PYTHON-on:
 	# remove wrong *.pyc, see related bug https://bitbucket.org/gems4/chemicalfun/issues/1/please-support-stagedir
 	@${FIND} ${STAGEDIR} -name "*.pyc" -delete
 	@${FIND} ${STAGEDIR} -name __pycache__ -delete
 	# strip binary
 	@${STRIP_CMD} ${STAGEDIR}${PYTHON_SITELIBDIR}/thermofun/PyThermoFun${PYTHON_EXT_SUFFIX}.so
 
 .include <bsd.port.mk>
diff --git a/science/thermofun/distinfo b/science/thermofun/distinfo
index b37f2129f913..59f3dc735b4f 100644
--- a/science/thermofun/distinfo
+++ b/science/thermofun/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1721889621
-SHA256 (thermohub-thermofun-v0.5.0_GH0.tar.gz) = 620f42a1f11753a0e6c5bfa8b9ce8b7319cd5582859da41f0fcddea4f60db536
-SIZE (thermohub-thermofun-v0.5.0_GH0.tar.gz) = 2087924
+TIMESTAMP = 1746512235
+SHA256 (thermohub-thermofun-v0.5.1_GH0.tar.gz) = 9f3bcd20112155f5b0d65e39768eceaef3f041485812c9211c281a318b3f057d
+SIZE (thermohub-thermofun-v0.5.1_GH0.tar.gz) = 2087867
diff --git a/science/thermofun/files/patch-python_thermofun_CMakeLists.txt b/science/thermofun/files/patch-python_thermofun_CMakeLists.txt
index 96ea83360240..1f43ef2f810b 100644
--- a/science/thermofun/files/patch-python_thermofun_CMakeLists.txt
+++ b/science/thermofun/files/patch-python_thermofun_CMakeLists.txt
@@ -1,20 +1,20 @@
---- python/thermofun/CMakeLists.txt.orig	2023-03-02 11:19:26 UTC
+--- python/thermofun/CMakeLists.txt.orig	2025-05-05 07:34:58 UTC
 +++ python/thermofun/CMakeLists.txt
 @@ -26,7 +26,7 @@ add_custom_target(thermofun ALL
      COMMAND ${CMAKE_COMMAND} -E copy $<TARGET_FILE:PyThermoFun> 
          ${CMAKE_CURRENT_BINARY_DIR}/$<TARGET_FILE_NAME:PyThermoFun>
      #COMMAND ${PYTHON_EXECUTABLE} -m pip install ${_PIP_ARG} -e ${CMAKE_CURRENT_BINARY_DIR}
 -    COMMAND ${PYTHON_EXECUTABLE} -m pip install --prefix ${CMAKE_BINARY_DIR} --ignore-installed .
 +    COMMAND ${PYTHON_EXECUTABLE} -m pip install --root ${FREEBSD_STAGEDIR} --prefix ${FREEBSD_PREFIX} --ignore-installed .
      WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR})
  
  # Set dependencies of thermofun target
-@@ -54,7 +54,7 @@ install(CODE
+@@ -71,7 +71,7 @@ install(CODE
      endif()
  
      execute_process(
--        COMMAND ${PYTHON_EXECUTABLE} -m pip install --prefix \${THERMOFUN_PYTHON_INSTALL_PREFIX_NATIVE} ${CMAKE_CURRENT_BINARY_DIR}
-+        COMMAND ${PYTHON_EXECUTABLE} -m pip install --root ${FREEBSD_STAGEDIR} --prefix ${FREEBSD_PREFIX} ${CMAKE_CURRENT_BINARY_DIR}
-         WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR})
+-        COMMAND \"${PYTHON_EXECUTABLE}\" -m pip install --prefix \"${THERMOFUN_PYTHON_INSTALL_PREFIX}\" \"${CMAKE_CURRENT_BINARY_DIR}\"
++        COMMAND \"${PYTHON_EXECUTABLE}\" -m pip install --root ${FREEBSD_STAGEDIR} --prefix ${FREEBSD_PREFIX} \"${CMAKE_CURRENT_BINARY_DIR}\"
+         WORKING_DIRECTORY \"${CMAKE_CURRENT_BINARY_DIR}\")
  "
  )