diff --git a/science/py-rmsd/Makefile b/science/py-rmsd/Makefile
index d9edf7efa270..5ce909f14539 100644
--- a/science/py-rmsd/Makefile
+++ b/science/py-rmsd/Makefile
@@ -1,20 +1,19 @@
 PORTNAME=	rmsd
-DISTVERSION=	1.4
-PORTREVISION=	1
+DISTVERSION=	1.5.1
 CATEGORIES=	science
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Calculate root-mean-square deviation (RMSD) between coordinate sets
 WWW=		https://github.com/charnley/rmsd
 
 LICENSE=	BSD2CLAUSE
 
 RUN_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}scipy>0:science/py-scipy@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	distutils autoplist concurrent
 
 .include <bsd.port.mk>
diff --git a/science/py-rmsd/distinfo b/science/py-rmsd/distinfo
index c91bc202a589..e9cacbf6dc7d 100644
--- a/science/py-rmsd/distinfo
+++ b/science/py-rmsd/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1605074347
-SHA256 (rmsd-1.4.tar.gz) = 16a84a5f919faa0f2361e55ad4009a7c28e19a21ee9cc3bdb83f28ffb566563f
-SIZE (rmsd-1.4.tar.gz) = 18001
+TIMESTAMP = 1731748655
+SHA256 (rmsd-1.5.1.tar.gz) = c0342821432aac10e98089877875a2cd8bbf624163971076d93686a40f10d127
+SIZE (rmsd-1.5.1.tar.gz) = 19076