diff --git a/databases/py-mysqlclient/Makefile b/databases/py-mysqlclient/Makefile
index b6f821e5370c..c73c8242fae6 100644
--- a/databases/py-mysqlclient/Makefile
+++ b/databases/py-mysqlclient/Makefile
@@ -1,27 +1,30 @@
 PORTNAME=	mysqlclient
-DISTVERSION=	2.1.1
+DISTVERSION=	2.2.0
 CATEGORIES=	databases python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	fluffy@FreeBSD.org
 COMMENT=	MySQL database connector for Python
 WWW=		https://pypi.org/project/mysqlclient
 
 LICENSE=	GPLv2
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-USES=		compiler:c11 iconv mysql python:3.7+ ssl
-USE_PYTHON=	autoplist concurrent distutils
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}setuptools>=49.2.0:devel/py-setuptools@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}wheel>=0.37:devel/py-wheel@${PY_FLAVOR}
+
+USES=		compiler:c11 iconv mysql pkgconfig python:3.7+ ssl
+USE_PYTHON=	autoplist concurrent pep517
 
 PORTDOCS=	*
 
 CONFLICTS=	py*-MySQLdb py*-MySQLdb5[0-9] py*-MySQLdb
 
 OPTIONS_DEFINE=		DOCS
 
 post-install-DOCS-on:
 	@${MKDIR} ${STAGEDIR}${DOCSDIR}
 	${INSTALL_DATA} ${WRKSRC}/README.md ${WRKSRC}/doc/* ${STAGEDIR}${DOCSDIR}
 
 .include <bsd.port.mk>
diff --git a/databases/py-mysqlclient/distinfo b/databases/py-mysqlclient/distinfo
index ef3f3e6fed73..31827594e35a 100644
--- a/databases/py-mysqlclient/distinfo
+++ b/databases/py-mysqlclient/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1656000526
-SHA256 (mysqlclient-2.1.1.tar.gz) = 828757e419fb11dd6c5ed2576ec92c3efaa93a0f7c39e263586d1ee779c3d782
-SIZE (mysqlclient-2.1.1.tar.gz) = 88138
+TIMESTAMP = 1687512745
+SHA256 (mysqlclient-2.2.0.tar.gz) = 04368445f9c487d8abb7a878e3d23e923e6072c04a6c320f9e0dc8a82efba14e
+SIZE (mysqlclient-2.2.0.tar.gz) = 89543