diff --git a/www/py-quilt3/Makefile b/www/py-quilt3/Makefile
index 47be0152c5b1..2e982793cc42 100644
--- a/www/py-quilt3/Makefile
+++ b/www/py-quilt3/Makefile
@@ -1,37 +1,37 @@
 PORTNAME=	quilt3
-PORTVERSION=	6.0.0
+PORTVERSION=	6.1.0
 CATEGORIES=	www python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	Python client for Quilt data hub
 WWW=		https://github.com/quiltdata/quilt
 
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}setuptools>=0:devel/py-setuptools@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}boto3>=1.21.7:www/py-boto3@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jsonlines>=1.2.0:devel/py-jsonlines@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jsonschema>=3<5:devel/py-jsonschema@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}platformdirs>=2:devel/py-platformdirs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pydantic2>=2.0.0<3.0.0:devel/py-pydantic2@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyyaml>=5.1:devel/py-pyyaml@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}requests>=2.12.4:www/py-requests@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}requests-futures>=1.0.0:www/py-requests-futures@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tenacity>=5.1.1:devel/py-tenacity@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tqdm>=4.32:misc/py-tqdm@${PY_FLAVOR}
 
 USES=		python:3.9+
 USE_PYTHON=	autoplist concurrent pep517
 
 NO_ARCH=	yes
 
 OPTIONS_DEFINE=	ANNDATA
 ANNDATA_DESC=	Annotated data support
 
 ANNDATA_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}anndata>=0.8.0:devel/py-anndata@${PY_FLAVOR}
 
 .include <bsd.port.mk>
diff --git a/www/py-quilt3/distinfo b/www/py-quilt3/distinfo
index dd27083b2012..df7b1981f24a 100644
--- a/www/py-quilt3/distinfo
+++ b/www/py-quilt3/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1725559911
-SHA256 (quilt3-6.0.0.tar.gz) = dd0be933f776ebfc183e44e6a918d302b2c797e4884b76386b780ee3b4950808
-SIZE (quilt3-6.0.0.tar.gz) = 98839
+TIMESTAMP = 1729509170
+SHA256 (quilt3-6.1.0.tar.gz) = aed2314629b67cdcd5dc82ec5b20d10b9b489069c909f9080669d31781a9437e
+SIZE (quilt3-6.1.0.tar.gz) = 103589