diff --git a/science/py-pymbd/Makefile b/science/py-pymbd/Makefile
index 6235ee43c814..56fab933982f 100644
--- a/science/py-pymbd/Makefile
+++ b/science/py-pymbd/Makefile
@@ -1,30 +1,38 @@
 PORTNAME=	pymbd
-DISTVERSION=	0.12.5
-PORTREVISION=	2
+DISTVERSION=	0.15.0
 CATEGORIES=	science # chemistry
 MASTER_SITES=	https://github.com/libmbd/libmbd/releases/download/${DISTVERSION}/
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Many-body dispersion library
 WWW=		https://github.com/libmbd/libmbd
 
 LICENSE=	MPL20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cffi>:devel/py-cffi@${PY_FLAVOR}
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cffi>=1:devel/py-cffi@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}poetry-core>0:devel/py-poetry-core@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}poetry-dynamic-versioning>0:devel/py-poetry-dynamic-versioning@${PY_FLAVOR} \
+		${PY_SETUPTOOLS}
 LIB_DEPENDS=	libmbd.so:science/libmbd
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cffi>:devel/py-cffi@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cffi>=1:devel/py-cffi@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}numpy>=1.20,1:math/py-numpy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}scipy>=1.6:science/py-scipy@${PY_FLAVOR}
 
-USES=		localbase python
-USE_PYTHON=	distutils autoplist
+USES=		localbase python shebangfix
+USE_PYTHON=	pep517 autoplist
+
+SHEBANG_FILES=	src/pymbd/benchmark.py
+
+MAKE_ENV=	LIBMBD_PREFIX=${LOCALBASE}
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 post-install: # strip binary
 	@${STRIP_CMD} ${STAGEDIR}${PYTHON_SITELIBDIR}/${PORTNAME}/_libmbd.abi3.so
 
 do-test: # also see https://github.com/libmbd/libmbd/issues/44
 	@${SETENV} ${TEST_ENV} ${PYTHON_CMD} ${FILESDIR}/example.py
 
 .include <bsd.port.mk>
diff --git a/science/py-pymbd/distinfo b/science/py-pymbd/distinfo
index 30185025db76..ea8ff61d9c1a 100644
--- a/science/py-pymbd/distinfo
+++ b/science/py-pymbd/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1659547712
-SHA256 (pymbd-0.12.5.tar.gz) = ca13375f8f4051380e7833bd3dd7c03780b3e2064fa96ec0da80b3fd7adfae78
-SIZE (pymbd-0.12.5.tar.gz) = 31229
+TIMESTAMP = 1785091863
+SHA256 (pymbd-0.15.0.tar.gz) = 94715e7d190eecc0b32f66fab70641201a8dfd58d51b3378d91c0d41ee259007
+SIZE (pymbd-0.15.0.tar.gz) = 34460