diff --git a/science/smoldyn/Makefile b/science/smoldyn/Makefile
index 1fa54051f7f4..2be7d6819c4b 100644
--- a/science/smoldyn/Makefile
+++ b/science/smoldyn/Makefile
@@ -1,28 +1,28 @@
 PORTNAME=	smoldyn
-DISTVERSION=	2.64
+DISTVERSION=	2.65
 CATEGORIES=	science
 MASTER_SITES=	http://www.smoldyn.org/
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Biochemical simulator for molecular diffusion, surface interactions
 
 LICENSE=	LGPL3
 LICENSE_FILE=	${WRKSRC}/License.txt
 
 LIB_DEPENDS=	libtiff.so:graphics/tiff
 
 USES=		cmake compiler:c++11-lang gl tar:tgz xorg
 USE_GL=		gl glu glut
 USE_XORG=	xi xmu
 USE_LDCONFIG=	yes
 
 CMAKE_OFF=	OPTION_PYTHON
 
 PLIST_FILES=	bin/${PORTNAME} \
 		include/libsmoldyn.h \
 		include/smoldyn.h \
 		include/smoldynconfigure.h \
 		lib/libsmoldyn_shared.so \
 		lib/libsmoldyn_static.a
 
 .include <bsd.port.mk>
diff --git a/science/smoldyn/distinfo b/science/smoldyn/distinfo
index 4d38f2ec9575..411f2c51d332 100644
--- a/science/smoldyn/distinfo
+++ b/science/smoldyn/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1616666096
-SHA256 (smoldyn-2.64.tgz) = ef463dfd5bf92ab55141c6f0d67c4c43f5394cc2e78a79992dd9fd10ed53ddfb
-SIZE (smoldyn-2.64.tgz) = 30163544
+TIMESTAMP = 1621590906
+SHA256 (smoldyn-2.65.tgz) = d18c8e3d932973b8ba260235689949e5f43bdb6936870a6a155ae9f5e1991568
+SIZE (smoldyn-2.65.tgz) = 30318941