diff --git a/science/py-avogadrolibs/Makefile b/science/py-avogadrolibs/Makefile
index 512758b56981..31fbec7c419d 100644
--- a/science/py-avogadrolibs/Makefile
+++ b/science/py-avogadrolibs/Makefile
@@ -1,32 +1,32 @@
 PORTNAME=	avogadrolibs
-DISTVERSION=	1.99.0
+DISTVERSION=	1.100.0
 CATEGORIES=	science
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Python bindings for Avogadro2 chemistry libraries
 WWW=		https://two.avogadro.cc/
 
 LICENSE=	GPLv2
 LICENSE_FILE=	${WRKSRC}/../LICENSE
 
 BUILD_DEPENDS=	${LOCALBASE}/include/pybind11/pybind11.h:devel/pybind11
 LIB_DEPENDS=	libAvogadroCore.so:science/avogadrolibs
 
 USES=		cmake compiler:c++11-lang eigen:3 python
 USE_PYTHON=	flavors
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	OpenChemistry
 
 WRKSRC_SUBDIR=	python
 
 CMAKE_ARGS=	-DINSTALL_LIBRARY_DIR:STRING=${PYTHON_SITELIBDIR}
 
 PLIST_FILES=	${PYTHON_SITELIBDIR}/avogadro/__init__.py \
 		${PYTHON_SITELIBDIR}/avogadro/cjson.py \
 		${PYTHON_SITELIBDIR}/avogadro/connect.py \
 		${PYTHON_SITELIBDIR}/avogadro/core${PYTHON_EXT_SUFFIX}.so \
 		${PYTHON_SITELIBDIR}/avogadro/io${PYTHON_EXT_SUFFIX}.so
 
 .include <bsd.port.mk>
diff --git a/science/py-avogadrolibs/distinfo b/science/py-avogadrolibs/distinfo
index 1955572e221d..0937050ab5aa 100644
--- a/science/py-avogadrolibs/distinfo
+++ b/science/py-avogadrolibs/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1707762010
-SHA256 (OpenChemistry-avogadrolibs-1.99.0_GH0.tar.gz) = 34808e3c602b0f60f3c160ff0220832aee777db86e962e3f958c6327fb434063
-SIZE (OpenChemistry-avogadrolibs-1.99.0_GH0.tar.gz) = 4858298
+TIMESTAMP = 1737595090
+SHA256 (OpenChemistry-avogadrolibs-1.100.0_GH0.tar.gz) = dd836d7287776a08673e664923960d13d222c5d630d1653bd182606e644de23c
+SIZE (OpenChemistry-avogadrolibs-1.100.0_GH0.tar.gz) = 4979722