diff --git a/devel/py-tox/Makefile b/devel/py-tox/Makefile
index 8d7d7d7e802b..8e4eda24edef 100644
--- a/devel/py-tox/Makefile
+++ b/devel/py-tox/Makefile
@@ -1,37 +1,37 @@
 PORTNAME=	tox
-DISTVERSION=	4.42.0
+DISTVERSION=	4.43.0
 CATEGORIES=	devel python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	bofh@FreeBSD.org
 COMMENT=	Virtualenv-based automation of test activities
 WWW=		https://tox.readthedocs.org/
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}hatch-vcs>=0.5:devel/py-hatch-vcs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hatchling>=1.28:devel/py-hatchling@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cachetools>=7.0.1:devel/py-cachetools@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}chardet>=5.2:textproc/py-chardet@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}colorama>=0.4.6:devel/py-colorama@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}filelock>=3.24:sysutils/py-filelock@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}packaging>=26:devel/py-packaging@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}platformdirs>=4.9.1:devel/py-platformdirs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pluggy>=1.6:devel/py-pluggy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyproject-api>=1.10:devel/py-pyproject-api@${PY_FLAVOR} \
 		${PY_TOMLI} \
 		${PY_TYPING_EXTENSIONS} \
 		${PYTHON_PKGNAMEPREFIX}virtualenv>=20.36.1:devel/py-virtualenv@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	autoplist concurrent pep517
 
 NO_ARCH=	yes
 
 # tox.ini clobbers our pytest arguments
 post-extract:
 	${RM} ${WRKSRC}/tox.ini
 
 .include <bsd.port.mk>
diff --git a/devel/py-tox/distinfo b/devel/py-tox/distinfo
index edb669e1fb8d..e42ea871a3ac 100644
--- a/devel/py-tox/distinfo
+++ b/devel/py-tox/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1788292471
-SHA256 (tox-4.42.0.tar.gz) = 5e018e281496fee16f860b5685adac8de14a42c9b2ad6c13df5632307ec9ea4f
-SIZE (tox-4.42.0.tar.gz) = 238505
+TIMESTAMP = 1788538495
+SHA256 (tox-4.43.0.tar.gz) = fbb35f32ef628c57eda168b448829050f987f4d6f153fa2b87c4238e19ab4bd7
+SIZE (tox-4.43.0.tar.gz) = 240878