diff --git a/biology/py-pyrodigal/Makefile b/biology/py-pyrodigal/Makefile
index 490813e388a2..69fe87cb7ad2 100644
--- a/biology/py-pyrodigal/Makefile
+++ b/biology/py-pyrodigal/Makefile
@@ -1,33 +1,33 @@
 PORTNAME=	pyrodigal
 DISTVERSION=	3.6.3
 CATEGORIES=	biology python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Python binding for Prodigal, an ORF finder for genomes and metagenomes
 WWW=		https://pyrodigal.readthedocs.io/en/stable/ \
-		https://github.com/althonos/pyrodigal/
+		https://github.com/althonos/pyrodigal
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cython3>0:lang/cython3@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scikit-build-core>0:devel/py-scikit-build-core@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}archspec>0:devel/py-archspec@${PY_FLAVOR}
 
 USES=		cmake:indirect python
 USE_PYTHON=	pep517 concurrent autoplist pytest # cython: cython3 isn't yet supported by python.mk
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 xpost-build:
 	@cd ${BUILD_WRKSRC} && ${SETENV} ${MAKE_ENV} ${PYTHON_CMD} setup.py build_ext --inplace
 
 post-install:
 	@${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/pyrodigal/lib${PYTHON_EXT_SUFFIX}.so
 
 do-test: # as of 3.6.3 this doesn't work: https://github.com/althonos/pyrodigal/issues/63
 	@cd ${TEST_WRKSRC} && ${SETENV} ${TEST_ENV} ${PYTHON_CMD} -m unittest discover -vv
 
 .include <bsd.port.mk>
diff --git a/biology/py-pyrodigal/files/patch-pyproject.toml b/biology/py-pyrodigal/files/patch-pyproject.toml
new file mode 100644
index 000000000000..097ac58992f9
--- /dev/null
+++ b/biology/py-pyrodigal/files/patch-pyproject.toml
@@ -0,0 +1,12 @@
+- workaround for https://github.com/althonos/pyrodigal/issues/69
+
+--- pyproject.toml.orig	2025-03-03 20:52:28 UTC
++++ pyproject.toml
+@@ -12,7 +12,6 @@ authors = [
+ authors = [
+   { name = "Martin Larralde", email = "martin.larralde@embl.de" },
+ ]
+-platform = "any"
+ keywords = ["bioinformatics", "genome", "orf", "gene", "prodigal"]
+ classifiers = [
+     "Development Status :: 5 - Production/Stable",