diff --git a/devel/py-grpcio-tools/Makefile b/devel/py-grpcio-tools/Makefile
index 0042289848d4..388cb1f7f643 100644
--- a/devel/py-grpcio-tools/Makefile
+++ b/devel/py-grpcio-tools/Makefile
@@ -1,25 +1,25 @@
 # Created by: vanilla@
 
 PORTNAME=	grpcio-tools
-PORTVERSION=	1.43.0
+PORTVERSION=	1.46.0
 CATEGORIES=	devel python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	vanilla@FreeBSD.org
 COMMENT=	Protobuf code generator for gRPC
 
 LICENSE=	BSD3CLAUSE
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}grpcio>1:devel/py-grpcio@${PY_FLAVOR}
 LIB_DEPENDS=	libcares.so:dns/c-ares
 
 USES=		compiler:c++11-lang localbase:ldflags python:3.5+
 USE_PYTHON=	autoplist distutils
 CFLAGS+=	-DHAVE_PTHREAD=1
 LDFLAGS+=	-lcares
 
 post-install:
 	${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/grpc_tools/_protoc_compiler*.so
 
 .include <bsd.port.mk>
diff --git a/devel/py-grpcio-tools/distinfo b/devel/py-grpcio-tools/distinfo
index 0a04d61785c5..0c2a5c961e5e 100644
--- a/devel/py-grpcio-tools/distinfo
+++ b/devel/py-grpcio-tools/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1639897365
-SHA256 (grpcio-tools-1.43.0.tar.gz) = f42f1d713096808b1b0472dd2a3749b712d13f0092dab9442d9c096446e860b2
-SIZE (grpcio-tools-1.43.0.tar.gz) = 2210483
+TIMESTAMP = 1652852498
+SHA256 (grpcio-tools-1.46.0.tar.gz) = 9295bf9b1e6dd5bcb260d594745fa3d6a089daade28f3a80cb2bc976b5359b7d
+SIZE (grpcio-tools-1.46.0.tar.gz) = 2230807