diff --git a/misc/py-bitsandbytes/Makefile b/misc/py-bitsandbytes/Makefile
index 574fbfdb1c00..cbbd90b59e68 100644
--- a/misc/py-bitsandbytes/Makefile
+++ b/misc/py-bitsandbytes/Makefile
@@ -1,36 +1,37 @@
 PORTNAME=	bitsandbytes
-DISTVERSION=	0.47.0
-PORTREVISION=	2
+DISTVERSION=	0.50.0
 CATEGORIES=	misc # machine-learning
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	k-bit optimizers and matrix multiplication routines
 WWW=		https://huggingface.co/docs/bitsandbytes/main/en/index \
 		https://github.com/bitsandbytes-foundation/bitsandbytes
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PY_SETUPTOOLS} \
 		${PYTHON_PKGNAMEPREFIX}scikit-build-core>0:devel/py-scikit-build-core@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}trove-classifiers>=2025.8.6.13:devel/py-trove-classifiers@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.16:math/py-numpy@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}pytorch>0:misc/py-pytorch@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.17:math/py-numpy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}packaging>=20.9:devel/py-packaging@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}pytorch>=2.4:misc/py-pytorch@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}einops>=0.8.0:misc/py-einops@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}lion-pytorch>=0.2.3:misc/py-lion-pytorch@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scipy>=1.11.4:science/py-scipy@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}transformers>=4.30.1<5:misc/py-transformers@${PY_FLAVOR}
+		${PYTHON_PKGNAMEPREFIX}transformers>=4.30.1:misc/py-transformers@${PY_FLAVOR}
 
 USES=		cmake:indirect python
 USE_PYTHON=	pep517 autoplist pytest
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	bitsandbytes-foundation
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 post-install:
 	@${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/bitsandbytes/libbitsandbytes_cpu.so
 
 .include <bsd.port.mk>
diff --git a/misc/py-bitsandbytes/distinfo b/misc/py-bitsandbytes/distinfo
index 26589b220b5f..5a146a2bfafe 100644
--- a/misc/py-bitsandbytes/distinfo
+++ b/misc/py-bitsandbytes/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1758248173
-SHA256 (bitsandbytes-foundation-bitsandbytes-0.47.0_GH0.tar.gz) = 3c6a85e53f64bc2c3f22429f237c7aa524e85e6a120bab7d6435384cd2f7a8ea
-SIZE (bitsandbytes-foundation-bitsandbytes-0.47.0_GH0.tar.gz) = 286187
+TIMESTAMP = 1784956328
+SHA256 (bitsandbytes-foundation-bitsandbytes-0.50.0_GH0.tar.gz) = 6d3820f5f235dbd4859cc7f34998ec792f3fc92e4cb93ec981b1fdc53dd54826
+SIZE (bitsandbytes-foundation-bitsandbytes-0.50.0_GH0.tar.gz) = 408443
diff --git a/misc/py-bitsandbytes/files/patch-pyproject.toml b/misc/py-bitsandbytes/files/patch-pyproject.toml
new file mode 100644
index 000000000000..cd8684a3068b
--- /dev/null
+++ b/misc/py-bitsandbytes/files/patch-pyproject.toml
@@ -0,0 +1,18 @@
+--- pyproject.toml.orig	2026-07-25 05:16:18 UTC
++++ pyproject.toml
+@@ -1,5 +1,5 @@
+ [build-system]
+-requires = ["scikit-build-core", "setuptools >= 77.0.3", "trove-classifiers>=2025.8.6.13"]
++requires = ["scikit-build-core", "setuptools", "trove-classifiers>=2025.8.6.13"]
+ build-backend = "scikit_build_core.setuptools.build_meta"
+ 
+ [project]
+@@ -13,8 +13,6 @@ readme = "README.md"
+ ]
+ requires-python = ">=3.10"
+ readme = "README.md"
+-license = "MIT"
+-license-files = ["LICENSE"]
+ keywords = [
+     "gpu",
+     "optimizers",