diff --git a/devel/py-cloudpickle/Makefile b/devel/py-cloudpickle/Makefile
index dba87aa624c7..64d92ad9e99c 100644
--- a/devel/py-cloudpickle/Makefile
+++ b/devel/py-cloudpickle/Makefile
@@ -1,26 +1,26 @@
 PORTNAME=	cloudpickle
-PORTVERSION=	2.2.0
+PORTVERSION=	2.2.1
 CATEGORIES=	devel python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	Extended pickling support for Python objects
 WWW=		https://github.com/cloudpipe/cloudpickle
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=0,1:math/py-numpy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}psutil>=0:sysutils/py-psutil@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tornado>=0:www/py-tornado@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}typing-extensions>=0:devel/py-typing-extensions@${PY_FLAVOR}
 
 USES=		python:3.8+
 USE_PYTHON=	autoplist concurrent distutils pytest
 
 NO_ARCH=	yes
 TEST_ARGS=	-s # https://github.com/cloudpipe/cloudpickle/issues/252
 TEST_ENV=	PYTHONPATH=tests/cloudpickle_testpkg
 
 .include <bsd.port.mk>
diff --git a/devel/py-cloudpickle/distinfo b/devel/py-cloudpickle/distinfo
index 2acbce698c5f..39421b869161 100644
--- a/devel/py-cloudpickle/distinfo
+++ b/devel/py-cloudpickle/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1662820060
-SHA256 (cloudpickle-2.2.0.tar.gz) = 3f4219469c55453cfe4737e564b67c2a149109dabf7f242478948b895f61106f
-SIZE (cloudpickle-2.2.0.tar.gz) = 59630
+TIMESTAMP = 1675190993
+SHA256 (cloudpickle-2.2.1.tar.gz) = d89684b8de9e34a2a43b3460fbca07d09d6e25ce858df4d5a44240403b6178f5
+SIZE (cloudpickle-2.2.1.tar.gz) = 60800