diff --git a/math/py-ml-dtypes/Makefile b/math/py-ml-dtypes/Makefile
index 000fa69c248f..63b27391cb34 100644
--- a/math/py-ml-dtypes/Makefile
+++ b/math/py-ml-dtypes/Makefile
@@ -1,27 +1,27 @@
 PORTNAME=	ml-dtypes
 PORTVERSION=	0.5.1
 PORTREVISION=	2
 CATEGORIES=	math python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DISTNAME=	ml_dtypes-${PORTVERSION}
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	Stand-alone implementation of several NumPy dtype extensions
 WWW=		https://github.com/jax-ml/ml_dtypes
 
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.26.0,1:math/py-numpy@${PY_FLAVOR} \
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=2.0,1<3,1:math/py-numpy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}setuptools>=0:devel/py-setuptools@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.26.0,1:math/py-numpy@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=2.1.0,1:math/py-numpy@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	autoplist concurrent pep517
 
 post-install:
 	${FIND} ${STAGEDIR}${PYTHON_SITELIBDIR} -name '*.so' -exec ${STRIP_CMD} {} +
 
 .include <bsd.port.mk>
diff --git a/math/py-ml-dtypes/files/patch-pyproject.toml b/math/py-ml-dtypes/files/patch-pyproject.toml
index 5ce41da69d71..23cd5429a7c2 100644
--- a/math/py-ml-dtypes/files/patch-pyproject.toml
+++ b/math/py-ml-dtypes/files/patch-pyproject.toml
@@ -1,26 +1,11 @@
 --- pyproject.toml.orig	2025-01-07 02:25:37 UTC
 +++ pyproject.toml
-@@ -17,11 +17,7 @@ dependencies = [
- # pip dependencies of the project
- dependencies = [
-     # Ensure numpy release supports Python version.
--    "numpy>=1.21",
--    "numpy>=1.21.2; python_version>='3.10'",
--    "numpy>=1.23.3; python_version>='3.11'",
--    "numpy>=1.26.0; python_version>='3.12'",
--    "numpy>=2.1.0; python_version>='3.13'",
-+    "numpy>=1.26.0",
- ]
- 
- [project.urls]
-@@ -51,8 +47,8 @@ requires = [
- requires = [
+@@ -52,7 +52,7 @@ requires = [
      # We build against the most recent supported NumPy 2.0 release;
      # see https://github.com/numpy/numpy/issues/27265
--    "numpy~=2.0",
+     "numpy~=2.0",
 -    "setuptools~=75.7.0",
-+    "numpy>=1.26.0",
 +    "setuptools",
  ]
  build-backend = "setuptools.build_meta"