diff --git a/biology/rubygem-bio/Makefile b/biology/rubygem-bio/Makefile
index 0169e71eac46..5c3300113218 100644
--- a/biology/rubygem-bio/Makefile
+++ b/biology/rubygem-bio/Makefile
@@ -1,20 +1,20 @@
 PORTNAME=	bio
-PORTVERSION=	2.0.3
+PORTVERSION=	2.0.4
 CATEGORIES=	biology rubygems
 MASTER_SITES=	RG
 
 MAINTAINER=	ruby@FreeBSD.org
 COMMENT=	Integrated environment for Bioinformatics written in Ruby
 WWW=		http://bioruby.org/
 
 LICENSE=	BSD2CLAUSE RUBY
 LICENSE_COMB=	dual
 LICENSE_FILE_BSD2CLAUSE=${WRKSRC}/BSDL
 LICENSE_FILE_RUBY=	${WRKSRC}/COPYING
 
 USES=		gem
 USE_RUBY=	yes
 
 NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/biology/rubygem-bio/distinfo b/biology/rubygem-bio/distinfo
index 2c34f7e6cc30..6f71416b28e9 100644
--- a/biology/rubygem-bio/distinfo
+++ b/biology/rubygem-bio/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1641046852
-SHA256 (rubygem/bio-2.0.3.gem) = b931ed0c94498bacb8c7dbd87c680672dbbae059299a3be1ee8c9f2b56b5816f
-SIZE (rubygem/bio-2.0.3.gem) = 1354752
+TIMESTAMP = 1663673078
+SHA256 (rubygem/bio-2.0.4.gem) = a93744191c663545b7ca5445e5ba0ef34ad395dd855fec38d3fcd92866b75321
+SIZE (rubygem/bio-2.0.4.gem) = 1366016