diff --git a/biology/bcftools/Makefile b/biology/bcftools/Makefile
index 394d9b71e894..2498ae7421df 100644
--- a/biology/bcftools/Makefile
+++ b/biology/bcftools/Makefile
@@ -1,61 +1,60 @@
 # Created by: Reed A. Cartwright <cartwright@asu.edu>
 
 PORTNAME=	bcftools
-PORTVERSION=	1.14
-PORTREVISION=	1
+PORTVERSION=	1.15
 CATEGORIES=	biology
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Tools for manipulating next-generation sequencing data
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 LIB_DEPENDS=	libhts.so:biology/htslib
 TEST_DEPENDS=	bash:shells/bash
 RUN_DEPENDS=	bash:shells/bash
 
 USES=		autoreconf gmake localbase perl5 python:env shebangfix
 
 USE_GITHUB=	yes
 USE_PERL5=	test
 
 GH_ACCOUNT=	samtools
 GNU_CONFIGURE=	yes
 SHEBANG_FILES=	misc/* test/test.pl
 
 OPTIONS_DEFINE=		GPL
 GPL_DESC=		Enable modules that rely on GPL code
 OPTIONS_DEFAULT=	GPL
 
 GPL_LIB_DEPENDS=	libgsl.so:math/gsl
 
 .include <bsd.port.options.mk>
 
 .if ${PORT_OPTIONS:MGPL}
 MAKE_ENV+=	USE_GPL=1
 LICENSE+=	GPLv3
 LICENSE_COMB=	multi
 .endif
 
 TEST_TARGET=	test
 
 pre-configure:
 	@${REINPLACE_CMD} -e 's|@PORTVERSION@|${PORTVERSION}|g' \
 		${WRKSRC}/configure.ac
 
 post-install:
 	${MV} ${STAGEDIR}${PREFIX}/bin/color-chrs.pl \
 		${STAGEDIR}${PREFIX}/bin/color-chrs
 	${MV} ${STAGEDIR}${PREFIX}/bin/guess-ploidy.py\
 	       ${STAGEDIR}${PREFIX}/bin/guess-ploidy
 	${MV} /${STAGEDIR}${PREFIX}/bin/plot-roh.py \
 		${STAGEDIR}${PREFIX}/bin/plot-roh
 	${MV} ${STAGEDIR}${PREFIX}/bin/run-roh.pl \
 		${STAGEDIR}${PREFIX}/bin/run-roh
 	${MV} ${STAGEDIR}${PREFIX}/bin/vcfutils.pl \
 		${STAGEDIR}${PREFIX}/bin/vcfutils
 	${MV} ${STAGEDIR}${PREFIX}/bin/plot-vcfstats \
 		${STAGEDIR}${PREFIX}/bin/
 
 .include <bsd.port.mk>
diff --git a/biology/bcftools/distinfo b/biology/bcftools/distinfo
index 3963175133e2..7f2539d1f09b 100644
--- a/biology/bcftools/distinfo
+++ b/biology/bcftools/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1639849304
-SHA256 (samtools-bcftools-1.14_GH0.tar.gz) = c9a814b1f0a13af19b45283f039d01b524e011d870ac95cd92e6907c3d1db6d1
-SIZE (samtools-bcftools-1.14_GH0.tar.gz) = 3326994
+TIMESTAMP = 1645831748
+SHA256 (samtools-bcftools-1.15_GH0.tar.gz) = 6b263270c62b156d2604150ca7e64b06a80282e049759b2668de24cbce1b1946
+SIZE (samtools-bcftools-1.15_GH0.tar.gz) = 3347901