diff --git a/biology/py-PySCeS/Makefile b/biology/py-PySCeS/Makefile
index 5b9a584864ca..b9df2b8c0536 100644
--- a/biology/py-PySCeS/Makefile
+++ b/biology/py-PySCeS/Makefile
@@ -1,36 +1,36 @@
 PORTNAME=	PySCeS
-DISTVERSION=	1.0.0
+DISTVERSION=	1.0.1
 CATEGORIES=	biology python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DISTNAME=	${PORTNAME:tl}-${DISTVERSION}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Python Simulator for Cellular Systems
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENCE.txt
 
 PY_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}ipython>0:devel/ipython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}matplotlib>0:math/py-matplotlib@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}nose>0:devel/py-nose@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}python-libsbml>0:biology/py-python-libsbml@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scipy>0:science/py-scipy@${PY_FLAVOR}
 BUILD_DEPENDS=	${PY_DEPENDS}
 RUN_DEPENDS=	${PY_DEPENDS}
 
 USES=		fortran python
 USE_PYTHON=	distutils autoplist
 
 LDFLAGS+=	-lpython${PYTHON_VER} -shared # see https://github.com/PySCeS/pysces/issues/29
 
 post-install:
 	@${STRIP_CMD} \
 		${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/pysces/pitcon/pitcon.cpython-38.so \
 		${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/pysces/nleq2/nleq2.cpython-38.so
 
 do-test: install # from section 2.1 Loading PySCeS in http://pysces.sourceforge.net/pdf/userguide.pdf
 	@${PYTHON_CMD} -c "import pysces; pysces.test();"
 
 .include <bsd.port.mk>
diff --git a/biology/py-PySCeS/distinfo b/biology/py-PySCeS/distinfo
index fcf30746c775..54db52b531ec 100644
--- a/biology/py-PySCeS/distinfo
+++ b/biology/py-PySCeS/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1632167616
-SHA256 (pysces-1.0.0.tar.gz) = ceb0270ae9adcad60585168ca81d2b3f7ec9304d435e1d9644213ee708ac2ed0
-SIZE (pysces-1.0.0.tar.gz) = 1608434
+TIMESTAMP = 1645813981
+SHA256 (pysces-1.0.1.tar.gz) = 15c36120ea2c61f996548be28f7be9c875cfdf4f1c80c15fd308f693ed1b4633
+SIZE (pysces-1.0.1.tar.gz) = 1608891