diff --git a/x11-toolkits/py-wxpython/Makefile b/x11-toolkits/py-wxpython/Makefile
index 154dc821b438..53ff69453a9e 100644
--- a/x11-toolkits/py-wxpython/Makefile
+++ b/x11-toolkits/py-wxpython/Makefile
@@ -1,58 +1,54 @@
 PORTNAME=	wxpython
-DISTVERSION=	4.2.4
+DISTVERSION=	4.2.5
 CATEGORIES=	x11-toolkits python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DIST_SUBDIR=	python
 
-PATCH_SITES=	https://github.com/wxWidgets/Phoenix/commit/
-PATCHFILES=	afddb14f78b08a576930babd4dc645d8f3f94701.patch:-p1
-
 MAINTAINER=	desktop@FreeBSD.org
 COMMENT=	GUI toolkit for the Python programming language
 WWW=		https://www.wxpython.org
 
 LICENSE=	WXWINDOWS LGPL21+ GPLv2+
 LICENSE_COMB=	multi
 LICENSE_NAME_WXWINDOWS=	wxWindows Library Licence, Version 3.1
 LICENSE_FILE_WXWINDOWS=	${WRKSRC}/license/licence.txt
 LICENSE_PERMS_WXWINDOWS=	dist-mirror pkg-mirror auto-accept
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}requests>=2.26.0:www/py-requests@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}setuptools>=0:devel/py-setuptools@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
+		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR} \
+		${PY_TYPING_EXTENSIONS}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=0:math/py-numpy@${PY_FLAVOR} \
 		${PY_TYPING_EXTENSIONS}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}appdirs>=0:devel/py-appdirs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}requests>=2.26.0:www/py-requests@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-xdist>=0:devel/py-pytest-xdist@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-forked>=0:devel/py-pytest-forked@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-timeout>=0:devel/py-pytest-timeout@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}sphinx>=0:textproc/py-sphinx@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}sphinxcontrib-jquery>=0:textproc/py-sphinxcontrib-jquery@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}beautifulsoup>=4:www/py-beautifulsoup@${PY_FLAVOR} \
 		${PY_TYPING_EXTENSIONS} \
 		${PYTHON_PKGNAMEPREFIX}numpy>=0:math/py-numpy@${PY_FLAVOR}
 
 USES=		compiler:c++11-lib localbase pkgconfig pyqt:6 python
 USE_WX=		3.2
 USE_PYQT=	sip:build sip:test
 USE_PYTHON=	autoplist cython pep517 pytest
 
-WRKSRC=		${WRKDIR}/wxPython-${DISTVERSION}
-
 # https://github.com/wxWidgets/Phoenix/issues/2819
 PEP517_BUILD_CMD=	${LOCALBASE}/bin/pyproject-build-${PYTHON_VER} --no-isolation --wheel ${PEP517_BUILD_CONFIG_SETTING}
 
 OPTIONS_DEFINE=		NLS
 
 NLS_USES=	gettext
 
 post-patch:
 	@${REINPLACE_CMD} -e 's|wx-config|${WX_CONFIG:T}|g' ${WRKSRC}/build.py
 	@${REINPLACE_CMD} -e 's|sip == 6.12.0|sip >= 6.12.0|' ${WRKSRC}/pyproject.toml
 
 post-install:
 	${FIND} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/wx -name "*.so" -exec ${STRIP_CMD} {} +
 
 .include <bsd.port.mk>
diff --git a/x11-toolkits/py-wxpython/distinfo b/x11-toolkits/py-wxpython/distinfo
index cd5e0fab824a..4bd1449e2a3f 100644
--- a/x11-toolkits/py-wxpython/distinfo
+++ b/x11-toolkits/py-wxpython/distinfo
@@ -1,5 +1,3 @@
-TIMESTAMP = 1769400596
-SHA256 (python/wxpython-4.2.4.tar.gz) = 2eb123979c87bcb329e8a2452269d60ff8f9f651e9bf25c67579e53c4ebbae3c
-SIZE (python/wxpython-4.2.4.tar.gz) = 58583054
-SHA256 (python/afddb14f78b08a576930babd4dc645d8f3f94701.patch) = 5f799a5507b56892e5a2160dd4f704e9606e6497392d93937e68637e7b51bf83
-SIZE (python/afddb14f78b08a576930babd4dc645d8f3f94701.patch) = 4990
+TIMESTAMP = 1771368220
+SHA256 (python/wxpython-4.2.5.tar.gz) = 44e836d1bccd99c38790bb034b6ecf70d9060f6734320560f7c4b0d006144793
+SIZE (python/wxpython-4.2.5.tar.gz) = 58732217
diff --git a/x11-toolkits/py-wxpython/files/patch-pyproject.toml b/x11-toolkits/py-wxpython/files/patch-pyproject.toml
index 6796bf577030..ec2c4339ec0e 100644
--- a/x11-toolkits/py-wxpython/files/patch-pyproject.toml
+++ b/x11-toolkits/py-wxpython/files/patch-pyproject.toml
@@ -1,20 +1,13 @@
 remove after setuptools update past 70.1
 
---- pyproject.toml.orig	2025-10-29 00:38:50 UTC
+--- pyproject.toml.orig	2026-02-08 15:20:31 UTC
 +++ pyproject.toml
-@@ -1,5 +1,5 @@
- [project]
--name = "wxPython"
-+name = "wxpython"
- description = "Cross platform GUI toolkit for Python, \"Phoenix\" version"
- requires-python = ">= 3.9"
- authors = [
 @@ -71,7 +71,7 @@ requires = [
  
  [build-system]
  requires = [
 -    "setuptools>=70.1",
 +    "setuptools",
      "cython >= 3.0.10",
      "requests >= 2.26.0",
      "sip == 6.12.0",