diff --git a/net/rubygem-grpc/Makefile b/net/rubygem-grpc/Makefile
index 4e525b90b978..76bfbce27cb1 100644
--- a/net/rubygem-grpc/Makefile
+++ b/net/rubygem-grpc/Makefile
@@ -1,30 +1,29 @@
 PORTNAME=	grpc
-PORTVERSION=	1.43.1
-PORTREVISION=	2
+PORTVERSION=	1.45.0
 CATEGORIES=	net rubygems
 MASTER_SITES=	RG
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	Ruby implementation of gRPC
 
 LICENSE=	BSD3CLAUSE
 
 LIB_DEPENDS=	libcares.so:dns/c-ares \
 		libgrpc.so:devel/grpc
 RUN_DEPENDS=	ca_root_nss>=0:security/ca_root_nss \
-		rubygem-google-protobuf>=3.18<4:devel/rubygem-google-protobuf \
+		rubygem-google-protobuf>=3.19<4:devel/rubygem-google-protobuf \
 		rubygem-googleapis-common-protos-types>=1.0<2:devel/rubygem-googleapis-common-protos-types
 
 USES=		cpe gem gmake pkgconfig
 USE_RUBY=	yes
 
 MAKE_JOBS_UNSAFE=	yes
 
 post-patch:
 	@${RM} ${WRKSRC}/Makefile ${WRKSRC}/.yardopts
 	@${RM} -r ${WRKSRC}/etc ${WRKSRC}/include ${WRKSRC}/third_party ${WRKSRC}/src/boringssl ${WRKSRC}/src/core
 	@${REINPLACE_CMD} -e 's|%%LOCALBASE%%|${LOCALBASE}|' ${WRKSRC}/src/ruby/lib/grpc.rb
 	@${REINPLACE_CMD} -Ee '/s\.files = /s;, "(Makefile|etc|include|third_party|src/boringssl|src/core)[^"]*"\.freeze;;g' ${WRKSRC}/${GEMSPEC}
 	@${REINPLACE_CMD} -e '/s\.files = /s|"\.yardopts"\.freeze, ||' ${WRKSRC}/${GEMSPEC}
 
 .include <bsd.port.mk>
diff --git a/net/rubygem-grpc/distinfo b/net/rubygem-grpc/distinfo
index 67941e8f3128..2b5c83311041 100644
--- a/net/rubygem-grpc/distinfo
+++ b/net/rubygem-grpc/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1643382630
-SHA256 (rubygem/grpc-1.43.1.gem) = 0abc081ae0ad2fa42689c6e2139f15f089d78d2e37b2a9e5055cab76c1c4dc87
-SIZE (rubygem/grpc-1.43.1.gem) = 5084672
+TIMESTAMP = 1649423952
+SHA256 (rubygem/grpc-1.45.0.gem) = 83e9ccf014d2b78ab372be19fb82617691c79cc4c9fc46fc5da272a6ce69f01e
+SIZE (rubygem/grpc-1.45.0.gem) = 5291008
diff --git a/net/rubygem-grpc/files/patch-src_ruby_ext_grpc_extconf.rb b/net/rubygem-grpc/files/patch-src_ruby_ext_grpc_extconf.rb
index 868b2f64b09a..74acc4494991 100644
--- a/net/rubygem-grpc/files/patch-src_ruby_ext_grpc_extconf.rb
+++ b/net/rubygem-grpc/files/patch-src_ruby_ext_grpc_extconf.rb
@@ -1,51 +1,65 @@
---- src/ruby/ext/grpc/extconf.rb.orig	2021-12-04 03:53:02 UTC
+--- src/ruby/ext/grpc/extconf.rb.orig	2022-04-11 16:34:02 UTC
 +++ src/ruby/ext/grpc/extconf.rb
 @@ -45,9 +45,9 @@ if darwin && !cross_compiling
    ENV['ARFLAGS'] = '-o'
  end
  
 -ENV['EMBED_OPENSSL'] = 'true'
 -ENV['EMBED_ZLIB'] = 'true'
 -ENV['EMBED_CARES'] = 'true'
 +ENV['EMBED_OPENSSL'] = 'false'
 +ENV['EMBED_ZLIB'] = 'false'
 +ENV['EMBED_CARES'] = 'false'
  
  ENV['ARCH_FLAGS'] = RbConfig::CONFIG['ARCH_FLAG']
  if darwin && !cross_compiling
-@@ -66,22 +66,23 @@ output_dir = File.expand_path(RbConfig::CONFIG['topdir
+@@ -66,29 +66,30 @@ output_dir = File.expand_path(RbConfig::CONFIG['topdir
  grpc_lib_dir = File.join(output_dir, 'libs', grpc_config)
  ENV['BUILDDIR'] = output_dir
  
 -unless windows
 -  puts 'Building internal gRPC into ' + grpc_lib_dir
 -  nproc = 4
--  nproc = Etc.nprocessors * 2 if Etc.respond_to? :nprocessors
+-  nproc = Etc.nprocessors if Etc.respond_to? :nprocessors
+-  nproc_override = ENV['GRPC_RUBY_BUILD_PROCS']
+-  unless nproc_override.nil? or nproc_override.size == 0
+-    nproc = nproc_override
+-    puts "Overriding make parallelism to #{nproc}"
+-  end
 -  make = bsd ? 'gmake' : 'make'
--  system("#{make} -j#{nproc} -C #{grpc_root} #{grpc_lib_dir}/libgrpc.a CONFIG=#{grpc_config} Q=")
+-  cmd = "#{make} -j#{nproc} -C #{grpc_root} #{grpc_lib_dir}/libgrpc.a CONFIG=#{grpc_config} Q="
+-  puts "Building grpc native library: #{cmd}"
+-  system(cmd)
 -  exit 1 unless $? == 0
 -end
 +#unless windows
 +#  puts 'Building internal gRPC into ' + grpc_lib_dir
 +#  nproc = 4
-+#  nproc = Etc.nprocessors * 2 if Etc.respond_to? :nprocessors
++#  nproc = Etc.nprocessors if Etc.respond_to? :nprocessors
++#  nproc_override = ENV['GRPC_RUBY_BUILD_PROCS']
++#  unless nproc_override.nil? or nproc_override.size == 0
++#    nproc = nproc_override
++#    puts "Overriding make parallelism to #{nproc}"
++#  end
 +#  make = bsd ? 'gmake' : 'make'
-+#  system("#{make} -j#{nproc} -C #{grpc_root} #{grpc_lib_dir}/libgrpc.a CONFIG=#{grpc_config} Q=")
++#  cmd = "#{make} -j#{nproc} -C #{grpc_root} #{grpc_lib_dir}/libgrpc.a CONFIG=#{grpc_config} Q="
++#  puts "Building grpc native library: #{cmd}"
++#  system(cmd)
 +#  exit 1 unless $? == 0
 +#end
  
 -$CFLAGS << ' -I' + File.join(grpc_root, 'include')
 +#$CFLAGS << ' -I' + File.join(grpc_root, 'include')
  
  ext_export_file = File.join(grpc_root, 'src', 'ruby', 'ext', 'grpc', 'ext-export')
 -$LDFLAGS << ' -Wl,--version-script="' + ext_export_file + '.gcc"' if linux
 -$LDFLAGS << ' -Wl,-exported_symbols_list,"' + ext_export_file + '.clang"' if darwin
 +#$LDFLAGS << ' -Wl,--version-script="' + ext_export_file + '.gcc"' if linux
 +#$LDFLAGS << ' -Wl,-exported_symbols_list,"' + ext_export_file + '.clang"' if darwin
  
 -$LDFLAGS << ' ' + File.join(grpc_lib_dir, 'libgrpc.a') unless windows
 +#$LDFLAGS << ' ' + File.join(grpc_lib_dir, 'libgrpc.a') unless windows
 +$LDFLAGS << ' -lgrpc' unless windows
  if grpc_config == 'gcov'
    $CFLAGS << ' -O0 -fprofile-arcs -ftest-coverage'
    $LDFLAGS << ' -fprofile-arcs -ftest-coverage -rdynamic'