diff --git a/biology/hmmer/Makefile b/biology/hmmer/Makefile
index f5097d816ada..8ecfa09c77f5 100644
--- a/biology/hmmer/Makefile
+++ b/biology/hmmer/Makefile
@@ -1,54 +1,53 @@
 PORTNAME=	hmmer
-PORTVERSION=	3.3.2
-PORTREVISION=	1
+DISTVERSION=	3.4
 CATEGORIES=	biology
 MASTER_SITES=	http://eddylab.org/software/hmmer/
 
 MAINTAINER=	mzaki@e-mail.ne.jp
 COMMENT=	Profile hidden Markov models for biological sequence analysis
 WWW=		http://hmmer.org/
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-ONLY_FOR_ARCHS=	amd64 i386 powerpc powerpc64
-ONLY_FOR_ARCHS_REASON=	requires SSE2 or AltiVec instructions
+ONLY_FOR_ARCHS=	aarch64 amd64 armv7 i386 powerpc powerpc64
+ONLY_FOR_ARCHS_REASON=	requires NEON, SSE2 or AltiVec instructions
 
 USES=		compiler:c11 gmake perl5 python:test shebangfix
 USE_PERL5=	test
 SHEBANG_FILES=	easel/devkit/*
 SHEBANG_GLOB=	*.pl *.py
 
 GNU_CONFIGURE=	yes
 GNU_CONFIGURE_MANPREFIX=${PREFIX}/share
 MAKE_ARGS=	V=1
 
 TEST_TARGET=	check
 
 OPTIONS_DEFINE=	DOCS EXAMPLES TEST
 
 DOCFILES=	Userguide.pdf
 EXAMPLES=	7LESS_DROME HBB_HUMAN MADE1.hmm MADE1.sto \
 		Pkinase.hmm Pkinase.sto dna_target.fa fn3.hmm fn3.sto \
 		globins4.hmm globins4.sto globins45.fa
 
 TEST_BUILD_DEPENDS=	${PYTHON_VERSION}:lang/python${PYTHON_SUFFIX}
 TEST_VARS=	use_perl5=build
 
 post-build-TEST-on:	pre-test do-test
 
 post-install:
 	@${STRIP_CMD} ${STAGEDIR}${PREFIX}/bin/*
 
 post-install-DOCS-on:
 	@${MKDIR} ${STAGEDIR}${DOCSDIR}
 	${INSTALL_DATA} ${DOCFILES:S,^,${WRKSRC}/,} ${STAGEDIR}${DOCSDIR}
 
 post-install-EXAMPLES-on:
 	@${MKDIR} ${STAGEDIR}${EXAMPLESDIR}
 	${INSTALL_DATA} ${EXAMPLES:S,^,${WRKSRC}/tutorial/,} ${STAGEDIR}${EXAMPLESDIR}
 
 pre-test:
 	${FIND} ${WRKSRC} -type f \( -name Makefile -or -name sqc \) -exec ${GREP} -q 'python3 ' {} \; -print | ${XARGS} ${SED} -i.bak 's/python3 /${PYTHON_VERSION} /'
 
 .include <bsd.port.mk>
diff --git a/biology/hmmer/distinfo b/biology/hmmer/distinfo
index edb75ddf6465..1c6cf4c9d3c9 100644
--- a/biology/hmmer/distinfo
+++ b/biology/hmmer/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1665491511
-SHA256 (hmmer-3.3.2.tar.gz) = 92fee9b5efe37a5276352d3502775e7c46e9f7a0ee45a331eacb2a0cac713c69
-SIZE (hmmer-3.3.2.tar.gz) = 18213049
+TIMESTAMP = 1729004147
+SHA256 (hmmer-3.4.tar.gz) = ca70d94fd0cf271bd7063423aabb116d42de533117343a9b27a65c17ff06fbf3
+SIZE (hmmer-3.4.tar.gz) = 19669667
diff --git a/biology/hmmer/pkg-plist b/biology/hmmer/pkg-plist
index 854e831b8df2..328699ae70d5 100644
--- a/biology/hmmer/pkg-plist
+++ b/biology/hmmer/pkg-plist
@@ -1,53 +1,52 @@
 bin/alimask
 bin/hmmalign
 bin/hmmbuild
 bin/hmmconvert
 bin/hmmemit
 bin/hmmfetch
 bin/hmmlogo
 bin/hmmpgmd
 bin/hmmpgmd_shard
 bin/hmmpress
 bin/hmmscan
 bin/hmmsearch
 bin/hmmsim
 bin/hmmstat
 bin/jackhmmer
 bin/makehmmerdb
 bin/nhmmer
 bin/nhmmscan
 bin/phmmer
 share/man/man1/alimask.1.gz
 share/man/man1/hmmalign.1.gz
 share/man/man1/hmmbuild.1.gz
-share/man/man1/hmmc2.1.gz
 share/man/man1/hmmconvert.1.gz
 share/man/man1/hmmemit.1.gz
 share/man/man1/hmmer.1.gz
 share/man/man1/hmmfetch.1.gz
 share/man/man1/hmmlogo.1.gz
 share/man/man1/hmmpgmd.1.gz
 share/man/man1/hmmpgmd_shard.1.gz
 share/man/man1/hmmpress.1.gz
 share/man/man1/hmmscan.1.gz
 share/man/man1/hmmsearch.1.gz
 share/man/man1/hmmsim.1.gz
 share/man/man1/hmmstat.1.gz
 share/man/man1/jackhmmer.1.gz
 share/man/man1/makehmmerdb.1.gz
 share/man/man1/nhmmer.1.gz
 share/man/man1/nhmmscan.1.gz
 share/man/man1/phmmer.1.gz
 %%PORTDOCS%%%%DOCSDIR%%/Userguide.pdf
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/7LESS_DROME
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/HBB_HUMAN
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/MADE1.hmm
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/MADE1.sto
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/Pkinase.hmm
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/Pkinase.sto
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/dna_target.fa
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/fn3.hmm
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/fn3.sto
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/globins4.hmm
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/globins4.sto
 %%PORTEXAMPLES%%%%EXAMPLESDIR%%/globins45.fa