diff --git a/biology/prodigy-lig/Makefile b/biology/prodigy-lig/Makefile
index 5ce38a831a96..c6982c31cff9 100644
--- a/biology/prodigy-lig/Makefile
+++ b/biology/prodigy-lig/Makefile
@@ -1,30 +1,31 @@
 PORTNAME=	prodigy-lig
 DISTVERSIONPREFIX=	v
-DISTVERSION=	1.1.3
-PORTREVISION=	2
+DISTVERSION=	1.1.4
 CATEGORIES=	biology python
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Prediction of protein-small molecule binding affinities
 WWW=		https://nestor.science.uu.nl/prodigy/lig
 
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.16:math/py-numpy@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR} \
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=2.0:math/py-numpy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}biopython>=1.79:biology/py-biopython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}poetry-core>0:devel/py-poetry-core@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}coverage>0:devel/py-coverage@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}hypothesis>0:devel/py-hypothesis@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}hypothesis>=6.100.1:devel/py-hypothesis@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-cov>0:devel/py-pytest-cov@${PY_FLAVOR}
 
 USES=		gmake python
 USE_PYTHON=	pep517 noflavors autoplist pytest
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	haddocking
 
 NO_ARCH=	yes
 
+# tests as of 1.1.4: 3 passed
+
 .include <bsd.port.mk>
diff --git a/biology/prodigy-lig/distinfo b/biology/prodigy-lig/distinfo
index 312bf1d82460..dbcdbebdaa12 100644
--- a/biology/prodigy-lig/distinfo
+++ b/biology/prodigy-lig/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1729012650
-SHA256 (haddocking-prodigy-lig-v1.1.3_GH0.tar.gz) = 2dc553beea82259feb5d1cce104f830e48c8b7d64a653818a3e49a84fbc68c64
-SIZE (haddocking-prodigy-lig-v1.1.3_GH0.tar.gz) = 157035
+TIMESTAMP = 1789172542
+SHA256 (haddocking-prodigy-lig-v1.1.4_GH0.tar.gz) = 95b64a964d7f95a48689f9edba22b5265f4c3b447516c3810445b32534e9bc31
+SIZE (haddocking-prodigy-lig-v1.1.4_GH0.tar.gz) = 176175