diff --git a/biology/hyphy/Makefile b/biology/hyphy/Makefile
index 5950895e7cc8..1c904fa426ba 100644
--- a/biology/hyphy/Makefile
+++ b/biology/hyphy/Makefile
@@ -1,24 +1,24 @@
 PORTNAME=	hyphy
-DISTVERSION=	2.5.32
+DISTVERSION=	2.5.33
 CATEGORIES=	biology
 
 MAINTAINER=	jrm@FreeBSD.org
 COMMENT=	Hypothesis testing using Phylogenies
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 ONLY_FOR_ARCHS=	aarch64 amd64 armv7 i386 powerpc64le powerpc64 powerpc
 
 LIB_DEPENDS=	libcurl.so:ftp/curl
 
 USES=		cmake localbase:ldflags
 USE_GITHUB=	yes
 GH_ACCOUNT=	veg
 
 OPTIONS_DEFINE=	AVX
 AVX_DESC=	Advanced vector extensions support
 
 AVX_CMAKE_OFF=	-DNOAVX:BOOL=ON
 
 .include <bsd.port.mk>
diff --git a/biology/hyphy/distinfo b/biology/hyphy/distinfo
index 948d3cd0569a..1da124f6cb84 100644
--- a/biology/hyphy/distinfo
+++ b/biology/hyphy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1629465228
-SHA256 (veg-hyphy-2.5.32_GH0.tar.gz) = e47be24b3de21a7a29eec6256cba7481ac8a98437d49eb682aefa5de2f4350ce
-SIZE (veg-hyphy-2.5.32_GH0.tar.gz) = 5346015
+TIMESTAMP = 1637149716
+SHA256 (veg-hyphy-2.5.33_GH0.tar.gz) = 7859981f645efa31911672803164715983068b3f56b597bc19908527639fa54b
+SIZE (veg-hyphy-2.5.33_GH0.tar.gz) = 5347184