diff --git a/biology/hisat2/files/patch-gfm.h b/biology/hisat2/files/patch-gfm.h
new file mode 100644
index 000000000000..6207decff165
--- /dev/null
+++ b/biology/hisat2/files/patch-gfm.h
@@ -0,0 +1,14 @@
+--- gfm.h.orig	2026-09-18 19:08:30 UTC
++++ gfm.h
+@@ -59,6 +59,11 @@
+ #include "repeat.h"
+ #include "repeat_kmer.h"
+ 
++#if defined(POPCNT_CAPABILITY) && !defined(__x86_64__) && !defined(__i386__) && \
++    !defined(_M_X64) && !defined(_M_IX86)
++#undef POPCNT_CAPABILITY
++#endif
++
+ #ifdef POPCNT_CAPABILITY
+ #include "processor_support.h"
+ #endif