diff --git a/science/py-asdf/Makefile b/science/py-asdf/Makefile
index 398ade237318..150580aa2496 100644
--- a/science/py-asdf/Makefile
+++ b/science/py-asdf/Makefile
@@ -1,58 +1,58 @@
 PORTNAME=	asdf
-PORTVERSION=	4.4.0
+PORTVERSION=	4.5.0
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	Python tools to handle ASDF files
 WWW=		https://www.asdf-format.org/projects/asdf/en/latest/ \
 		https://github.com/asdf-format/asdf
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}setuptools>=60:devel/py-setuptools@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}setuptools-scm>=3.4:devel/py-setuptools-scm@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}asdf-standard>=1.1.0:science/py-asdf-standard@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}asdf-transform-schemas>=0.3:science/py-asdf-transform-schemas@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}attrs>=22.2.0:devel/py-attrs@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jmespath>=0.6.2:devel/py-jmespath@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}numpy>=1.22,1:math/py-numpy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}packaging>=19:devel/py-packaging@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyyaml>=5.4.1:devel/py-pyyaml@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}semantic-version>=2.8:devel/py-semantic-version@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}fsspec>=2022.8.2:filesystems/py-fsspec@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}lz4>=0.10:archivers/py-lz4@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}psutil>=0:sysutils/py-psutil@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-doctestplus>=0:devel/py-pytest-doctestplus@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-remotedata>=0:devel/py-pytest-remotedata@${PY_FLAVOR}
 # fsspec[http]
 TEST_DEPENDS+=	${PYTHON_PKGNAMEPREFIX}aiohttp>=0:www/py-aiohttp@${PY_FLAVOR}
 
 USES=		python shebangfix
 USE_PYTHON=	autoplist concurrent pep517 pytest
 
 NO_ARCH=	yes
 
 SHEBANG_FILES=	asdf/_jsonschema/json/bin/jsonschema_suite
 
 OPTIONS_DEFINE=	ALL HTTP LZ4
 OPTIONS_DEFAULT=ALL HTTP LZ4
 ALL_IMPLIES=	HTTP LZ4
 ALL_DESC=	All optional dependencies
 HTTP_DESC=	HTTP support via fsspec
 LZ4_DESC=	Lz4 compression algorithm support
 
 HTTP_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}aiohttp>=0:www/py-aiohttp@${PY_FLAVOR} \
 			${PYTHON_PKGNAMEPREFIX}fsspec>=2022.8.2:filesystems/py-fsspec@${PY_FLAVOR}
 LZ4_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}lz4>=0.10:archivers/py-lz4@${PY_FLAVOR}
 
 .include <bsd.port.pre.mk>
 
 .if ${PYTHON_REL} < 31100
 RUN_DEPENDS+=	${PYTHON_PKGNAMEPREFIX}importlib-metadata>=4.11.4:devel/py-importlib-metadata@${PY_FLAVOR}
 .endif
 
 .include <bsd.port.post.mk>
diff --git a/science/py-asdf/distinfo b/science/py-asdf/distinfo
index f4e9bc88b54d..cf61646370fe 100644
--- a/science/py-asdf/distinfo
+++ b/science/py-asdf/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1757120806
-SHA256 (asdf-4.4.0.tar.gz) = f7146119e3d217f0b83d125e2fd657c1b2427caf6faeaf7ceedcd81db464363e
-SIZE (asdf-4.4.0.tar.gz) = 899576
+TIMESTAMP = 1757436539
+SHA256 (asdf-4.5.0.tar.gz) = 1f37979263cac53b8f7b078c521fda8aa9a08cd5d2badb9aacec34d6badd2dc1
+SIZE (asdf-4.5.0.tar.gz) = 900039