diff --git a/devel/spyder/Makefile b/devel/spyder/Makefile
index b3fdf4e0764a..bcf1d31e97aa 100644
--- a/devel/spyder/Makefile
+++ b/devel/spyder/Makefile
@@ -1,66 +1,66 @@
 PORTNAME=	spyder
 DISTVERSIONPREFIX=	v
-DISTVERSION=	5.4.2
+DISTVERSION=	5.4.3
 CATEGORIES=	devel science python
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Scientific PYthon Development EnviRonment, an alternative to IDLE
 WWW=		https://www.spyder-ide.org/
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
 RUN_DEPENDS=	\
 		${PYTHON_PKGNAMEPREFIX}atomicwrites>=1.2.0:devel/py-atomicwrites@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}chardet>=2.0.0:textproc/py-chardet@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}cloudpickle>=0.5.0:devel/py-cloudpickle@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}cookiecutter>=1.6.0:devel/py-cookiecutter@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}diff-match-patch>=20181111:textproc/py-diff-match-patch@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}intervaltree>=3.0.2:devel/py-intervaltree@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipython>=7.31.1:devel/ipython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jedi>=0.17.2:devel/py-jedi@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jellyfish>=0.7:devel/py-jellyfish@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jsonschema>=3.2.0:devel/py-jsonschema@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}keyring>=17.0.0:security/py-keyring@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}nbconvert>=4.0:devel/py-nbconvert@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}numpydoc>=0.6.0:textproc/py-numpydoc@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}parso>=0.7.0:textproc/py-parso@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pexpect>=4.4.0:misc/py-pexpect@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pickleshare>=0.4:databases/py-pickleshare@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}psutil>=5.3:sysutils/py-psutil@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pygments>=2.0:textproc/py-pygments@${PY_FLAVOR} \
 		pylint${PYTHON_PKGNAMESUFFIX}>=2.5.0:devel/pylint@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pylint-venv>=2.1.1:devel/py-pylint-venv@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}python-lsp-black>=1.2.0:textproc/py-python-lsp-black@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyls-spyder>=0.4.0:textproc/py-pyls-spyder@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}qt5-webengine>0:www/py-qt5-webengine@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}python-lsp-server>0:textproc/py-python-lsp-server@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}xdg>=0.26:devel/py-xdg@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyzmq>=22.1.0:net/py-pyzmq@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}QDarkStyle>=3.0.2:textproc/py-QDarkStyle@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}qstylizer>=0.2.2:devel/py-qstylizer@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}QtAwesome>=1.2.1:x11-fonts/py-QtAwesome@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}qtconsole>=5.4.0:devel/py-qtconsole@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}QtPy>=2.1.0:devel/py-QtPy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}rtree>=0.9.7:devel/py-rtree@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}sphinx>=0.6.6:textproc/py-sphinx@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}spyder-kernels>=2.4.2:devel/py-spyder-kernels@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}textdistance>=4.2.0:textproc/py-textdistance@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}three-merge>=0.1.1:textproc/py-three-merge@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}watchdog>=0.10.3:devel/py-watchdog@${PY_FLAVOR}
 
 USES=		desktop-file-utils python:3.7+ pyqt:5
 USE_PYTHON=	distutils autoplist noflavors
 USE_PYQT=	pyqt5 sip
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	spyder-ide
 
 NO_ARCH=	yes
 
 DOCSDIR=	${PYTHON_SITELIBDIR}/spyder
 
 post-extract: # remove bundled dependencies
 	@${RM} -r ${WRKSRC}/external-deps/*
 
 .include <bsd.port.mk>
diff --git a/devel/spyder/distinfo b/devel/spyder/distinfo
index 52feda538016..6671bfeb3f0b 100644
--- a/devel/spyder/distinfo
+++ b/devel/spyder/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1679793033
-SHA256 (spyder-ide-spyder-v5.4.2_GH0.tar.gz) = 6011b9cd0a09c8393351548a299d4e0ffa2903a1f1fede7427ed78b89f35f0fc
-SIZE (spyder-ide-spyder-v5.4.2_GH0.tar.gz) = 24523453
+TIMESTAMP = 1681095371
+SHA256 (spyder-ide-spyder-v5.4.3_GH0.tar.gz) = 162ad8265bb7f81f232a162585d57665a8651704410d12f4173a5fe4366c6855
+SIZE (spyder-ide-spyder-v5.4.3_GH0.tar.gz) = 16207604
diff --git a/devel/spyder/files/patch-binder_environment.yml b/devel/spyder/files/patch-binder_environment.yml
index 168de394dc37..6f54f993caa0 100644
--- a/devel/spyder/files/patch-binder_environment.yml
+++ b/devel/spyder/files/patch-binder_environment.yml
@@ -1,15 +1,15 @@
---- binder/environment.yml.orig	2023-01-18 21:16:10 UTC
+--- binder/environment.yml.orig	2023-04-05 02:35:28 UTC
 +++ binder/environment.yml
-@@ -31,10 +31,10 @@ dependencies:
- - pyqt <5.16
- - pyqtwebengine <5.16
- - python-lsp-black >=1.2.0
--- python-lsp-server >=1.7.1,<1.8.0
-+- python-lsp-server >0
+@@ -34,10 +34,10 @@ dependencies:
+ - python-lsp-server >=1.7.2,<1.8.0
  - pyxdg >=0.26
  - pyzmq >=22.1.0
--- qdarkstyle >=3.0.2,<3.1.0
-+- qdarkstyle >=3.0.2
+-- qdarkstyle >=3.0.2,<3.2.0
++- qdarkstyle >0
  - qstylizer >=0.2.2
  - qtawesome >=1.2.1
- - qtconsole >=5.4.0,<5.5.0
+-- qtconsole >=5.4.2,<5.5.0
++- qtconsole >0
+ - qtpy >=2.1.0
+ - rtree >=0.9.7
+ - setuptools >=49.6.0
diff --git a/devel/spyder/files/patch-requirements_main.yml b/devel/spyder/files/patch-requirements_main.yml
index 2c2310dad432..127845885ef9 100644
--- a/devel/spyder/files/patch-requirements_main.yml
+++ b/devel/spyder/files/patch-requirements_main.yml
@@ -1,14 +1,15 @@
---- requirements/main.yml.orig	2023-01-18 21:16:10 UTC
+--- requirements/main.yml.orig	2023-04-05 02:35:28 UTC
 +++ requirements/main.yml
-@@ -29,9 +29,9 @@ dependencies:
-   - pyqt <5.16
-   - pyqtwebengine <5.16
+@@ -31,10 +31,10 @@ dependencies:
    - python-lsp-black >=1.2.0
--  - python-lsp-server >=1.7.1,<1.8.0
-+  - python-lsp-server
+   - python-lsp-server >=1.7.2,<1.8.0
    - pyzmq >=22.1.0
--  - qdarkstyle >=3.0.2,<3.1.0
-+  - qdarkstyle >=3.0.2
+-  - qdarkstyle >=3.0.2,<3.2.0
++  - qdarkstyle >0
    - qstylizer >=0.2.2
    - qtawesome >=1.2.1
-   - qtconsole >=5.4.0,<5.5.0
+-  - qtconsole >=5.4.2,<5.5.0
++  - qtconsole >0
+   - qtpy >=2.1.0
+   - rtree >=0.9.7
+   - setuptools >=49.6.0
diff --git a/devel/spyder/files/patch-setup.py b/devel/spyder/files/patch-setup.py
index e7b8cd97487f..0843883061a0 100644
--- a/devel/spyder/files/patch-setup.py
+++ b/devel/spyder/files/patch-setup.py
@@ -1,32 +1,32 @@
---- setup.py.orig	2023-01-18 21:16:10 UTC
+--- setup.py.orig	2023-04-05 02:35:28 UTC
 +++ setup.py
 @@ -91,7 +91,7 @@ def get_data_files():
      """
      Return data_files in a platform dependent manner.
      """
 -    if sys.platform.startswith('linux'):
 +    if sys.platform.startswith('linux') or sys.platform.startswith('freebsd'):
          data_files = [('share/applications', ['scripts/spyder.desktop']),
                        ('share/icons', ['img_src/spyder.png']),
                        ('share/metainfo',
 @@ -197,7 +197,6 @@ setup_args = dict(
          'Topic :: Scientific/Engineering',
          'Topic :: Software Development :: Widget Sets',
      ],
 -    cmdclass=CMDCLASS,
  )
  
  
-@@ -229,10 +228,10 @@ install_requires = [
-     'pyls-spyder>=0.4.0',
-     'pyqt5<5.16',
-     'pyqtwebengine<5.16',
--    'python-lsp-server[all]>=1.7.1,<1.8.0',
-+    'python-lsp-server[all]',
+@@ -232,10 +231,10 @@ install_requires = [
+     'python-lsp-server[all]>=1.7.2,<1.8.0',
      'pyxdg>=0.26;platform_system=="Linux"',
      'pyzmq>=22.1.0',
--    'qdarkstyle>=3.0.2,<3.1.0',
-+    'qdarkstyle>=3.0.2',
+-    'qdarkstyle>=3.0.2,<3.2.0',
++    'qdarkstyle>0',
      'qstylizer>=0.2.2',
      'qtawesome>=1.2.1',
-     'qtconsole>=5.4.0,<5.5.0',
+-    'qtconsole>=5.4.2,<5.5.0',
++    'qtconsole>0',
+     'qtpy>=2.1.0',
+     'rtree>=0.9.7',
+     'setuptools>=49.6.0',
diff --git a/devel/spyder/files/patch-spyder_dependencies.py b/devel/spyder/files/patch-spyder_dependencies.py
index 31eaedb84652..d815b5b81ffa 100644
--- a/devel/spyder/files/patch-spyder_dependencies.py
+++ b/devel/spyder/files/patch-spyder_dependencies.py
@@ -1,17 +1,15 @@
---- spyder/dependencies.py.orig	2023-01-18 21:16:10 UTC
+--- spyder/dependencies.py.orig	2023-04-05 02:35:28 UTC
 +++ spyder/dependencies.py
-@@ -53,12 +53,12 @@ PSUTIL_REQVER = '>=5.3'
- PYGMENTS_REQVER = '>=2.0'
- PYLINT_REQVER = '>=2.5.0;<3.0'
- PYLINT_VENV_REQVER = '>=2.1.1'
--PYLSP_REQVER = '>=1.7.1;<1.8.0'
-+PYLSP_REQVER = '>0'
- PYLSP_BLACK_REQVER = '>=1.2.0'
+@@ -58,10 +58,10 @@ PYLSP_BLACK_REQVER = '>=1.2.0'
  PYLS_SPYDER_REQVER = '>=0.4.0'
  PYXDG_REQVER = '>=0.26'
  PYZMQ_REQVER = '>=22.1.0'
--QDARKSTYLE_REQVER = '>=3.0.2;<3.1.0'
-+QDARKSTYLE_REQVER = '>=3.0.2'
+-QDARKSTYLE_REQVER = '>=3.0.2,<3.2.0'
++QDARKSTYLE_REQVER = '>0'
  QSTYLIZER_REQVER = '>=0.2.2'
  QTAWESOME_REQVER = '>=1.2.1'
- QTCONSOLE_REQVER = '>=5.4.0;<5.5.0'
+-QTCONSOLE_REQVER = '>=5.4.2,<5.5.0'
++QTCONSOLE_REQVER = '>0'
+ QTPY_REQVER = '>=2.1.0'
+ RTREE_REQVER = '>=0.9.7'
+ SETUPTOOLS_REQVER = '>=49.6.0'