diff --git a/science/py-DendroPy/Makefile b/science/py-DendroPy/Makefile
index ea1e13d34400..6d5738fa993c 100644
--- a/science/py-DendroPy/Makefile
+++ b/science/py-DendroPy/Makefile
@@ -1,16 +1,16 @@
 PORTNAME=	DendroPy
-PORTVERSION=	4.6.0
+PORTVERSION=	4.6.1
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	wen@FreeBSD.org
 COMMENT=	Phylogenetic computing library
 WWW=		http://packages.python.org/DendroPy/
 
 LICENSE=	BSD3CLAUSE
 
 USES=		python:3.7+
 USE_PYTHON=	distutils autoplist
 
 .include <bsd.port.mk>
diff --git a/science/py-DendroPy/distinfo b/science/py-DendroPy/distinfo
index 59cf6d5746d6..dd92d924dcca 100644
--- a/science/py-DendroPy/distinfo
+++ b/science/py-DendroPy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1685833884
-SHA256 (DendroPy-4.6.0.tar.gz) = a8fe2fc2e243aa89b01e8f8d5c51a4724cecdbc2e8de45e3fbaf8100dcf46b6f
-SIZE (DendroPy-4.6.0.tar.gz) = 15200578
+TIMESTAMP = 1686639965
+SHA256 (DendroPy-4.6.1.tar.gz) = 26fcbe1cb5831301e8f1f2e15a0563620f0b8e29e6d409dd6a2a7c957dd64c16
+SIZE (DendroPy-4.6.1.tar.gz) = 15200462