diff --git a/biology/py-dnaio/Makefile b/biology/py-dnaio/Makefile
index e473a1ccde21..16433ad5f3a8 100644
--- a/biology/py-dnaio/Makefile
+++ b/biology/py-dnaio/Makefile
@@ -1,21 +1,21 @@
 PORTNAME=	dnaio
-DISTVERSION=	1.2.0
+DISTVERSION=	1.2.1
 CATEGORIES=	biology python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
-MAINTAINER=	ports@FreeBSD.org
+MAINTAINER=	wen@FreeBSD.org
 COMMENT=	Read and write FASTQ and FASTA
 WWW=		https://pypi.python.org/pypi/dnaio
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PY_SETUPTOOLS} \
 		${PYTHON_PKGNAMEPREFIX}setuptools-scm>0:devel/py-setuptools-scm@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	autoplist cython pep517
 
 .include <bsd.port.mk>
diff --git a/biology/py-dnaio/distinfo b/biology/py-dnaio/distinfo
index 26a5cfc997eb..77aa2898910a 100644
--- a/biology/py-dnaio/distinfo
+++ b/biology/py-dnaio/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1707060534
-SHA256 (dnaio-1.2.0.tar.gz) = d0528c23516fe4e947970bdef33c423f0a30ab3b083bd4f6f049fd66d8cef803
-SIZE (dnaio-1.2.0.tar.gz) = 58225
+TIMESTAMP = 1720074321
+SHA256 (dnaio-1.2.1.tar.gz) = 4786dc63614b9f3011463d9ea9d981723dd38d1091a415a557f71d8c74400f38
+SIZE (dnaio-1.2.1.tar.gz) = 59274