diff --git a/science/py-scipy-stubs/Makefile b/science/py-scipy-stubs/Makefile
index 91c6f050d9ad..51c8e1cc2357 100644
--- a/science/py-scipy-stubs/Makefile
+++ b/science/py-scipy-stubs/Makefile
@@ -1,26 +1,27 @@
 PORTNAME=	scipy-stubs
-DISTVERSION=	1.18.0.1
+DISTVERSION=	1.18.1.0
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DISTNAME=	${PORTNAME:S/-/_/}-${PORTVERSION}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Type annotations for SciPy
 WWW=		https://scipy.org/ \
 		https://github.com/scipy/scipy-stubs
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}uv-build>=0.11.28:devel/py-uv-build@${PY_FLAVOR}
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}optype>=0.15.0:devel/py-optype@${PY_FLAVOR}
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}uv-build>=0.12.5:devel/py-uv-build@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>0:math/py-numpy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}optype>=0.15.0:devel/py-optype@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	autoplist concurrent pep517
 NO_ARCH=	yes
 
 post-extract:
 	@${REINPLACE_CMD} -e 's/^license = "\([^"]*\)"/license = {text = "\1"}/' -e '/^license-files/d' ${WRKSRC}/pyproject.toml
 
 .include <bsd.port.mk>
diff --git a/science/py-scipy-stubs/distinfo b/science/py-scipy-stubs/distinfo
index 4d9f4640383c..9443fc3ef115 100644
--- a/science/py-scipy-stubs/distinfo
+++ b/science/py-scipy-stubs/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1784567988
-SHA256 (scipy_stubs-1.18.0.1.tar.gz) = 761cb35106200c90a37034d3c8120d3899d673de1e5879d3a2ac1d6816c62327
-SIZE (scipy_stubs-1.18.0.1.tar.gz) = 410862
+TIMESTAMP = 1789395220
+SHA256 (scipy_stubs-1.18.1.0.tar.gz) = 87bec0df883cd9cd6b7dc4c74a33362cf550e9cad679643a29a886ab2b438ddc
+SIZE (scipy_stubs-1.18.1.0.tar.gz) = 448822
diff --git a/science/py-scipy-stubs/files/patch-pyproject.toml b/science/py-scipy-stubs/files/patch-pyproject.toml
index e3138131f915..7799e93f6c0d 100644
--- a/science/py-scipy-stubs/files/patch-pyproject.toml
+++ b/science/py-scipy-stubs/files/patch-pyproject.toml
@@ -1,9 +1,10 @@
--- Relax uv-build upper bound for devel/py-uv-build 0.12.0 compatibility.
+-- Relax uv-build upper bound so the port builds with the latest
+-- devel/py-uv-build package in the tree.
 
---- pyproject.toml.orig	2026-07-29 00:00:00 UTC
+--- pyproject.toml.orig	2026-09-14 14:59:07 UTC
 +++ pyproject.toml
 @@ -1,3 +1,3 @@
  [build-system]
--requires = ["uv_build>=0.11.28,<0.12"]
-+requires = ["uv_build>=0.11.28"]
+-requires = ["uv_build>=0.12.5,<0.13"]
++requires = ["uv_build>=0.12.5"]
  build-backend = "uv_build"