diff --git a/science/InsightToolkit521/Makefile b/science/InsightToolkit521/Makefile
index 56a498b90369..28a004098c4f 100644
--- a/science/InsightToolkit521/Makefile
+++ b/science/InsightToolkit521/Makefile
@@ -1,76 +1,76 @@
 PORTNAME=	InsightToolkit
 DISTVERSIONPREFIX=	v
 DISTVERSION=	5.2.1
 CATEGORIES=	science biology
 MASTER_SITES=	https://github.com/InsightSoftwareConsortium/ITK/releases/download/v${DISTVERSION}/:data
 PKGNAMESUFFIX=	521
 DISTFILES=	InsightData-${DISTVERSION}.tar.gz:data
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Insight Toolkit
 WWW=		https://www.itk.org
 
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
+BROKEN_i386=	compilation fails: always_inline function '_mm_cvtsd_si32' requires target feature 'sse2' (i386 doesn't have SSE2 enabled by default, and adding -msse2 doesn't help)
+
 BUILD_DEPENDS=	googletest>=0:devel/googletest
 LIB_DEPENDS=	libgdcmCommon.so:devel/gdcm \
 		libexpat.so:textproc/expat2 \
 		libfftw.so:math/fftw \
 		libhdf5.so:science/hdf5 \
 		libpng.so:graphics/png \
 		libsz.so:science/libaec \
 		libtiff.so:graphics/tiff
 
 USES=		cmake:testing compiler:c++11-lang eigen:3 jpeg pkgconfig python:test
 USE_LDCONFIG=	${PREFIX}/lib/InsightToolkit
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	InsightSoftwareConsortium
 GH_PROJECT=	ITK
 
 CMAKE_ON=	BUILD_SHARED_LIBS \
 		ITK_FORBID_DOWNLOADS \
 		ITK_LEGACY_SILENT \
 		ITK_USE_SYSTEM_EXPAT \
 		ITK_USE_SYSTEM_FFTW \
 		ITK_USE_SYSTEM_GDCM \
 		ITK_USE_SYSTEM_HDF5 \
 		ITK_USE_SYSTEM_JPEG \
 		ITK_USE_SYSTEM_LIBRARIES \
 		ITK_USE_SYSTEM_PNG \
 		ITK_USE_SYSTEM_TIFF \
 		ITK_USE_SYSTEM_ZLIB \
 		Module_ITKIOMIC \
 		Module_ITKIOTransformMINC \
 		Module_ITKReview
 CMAKE_ARGS=	-DPython3_EXECUTABLE=${PYTHON_CMD}
 CMAKE_OFF=	ITK_USE_KWSTYLE BUILD_TESTING
 CMAKE_TESTING_ON=	BUILD_TESTING # 3 tests are known to fail, see https://github.com/InsightSoftwareConsortium/ITK/issues/3739
 
-CXXFLAGS_i386=	-msse2 # to fix this error: always_inline function '_mm_cvtsd_si32' requires target feature 'sse2' (i386 doesn't have SSE2 enabled by default)
-
 ITK_VER=	${PORTVERSION:R}
 
 PLIST_SUB+=	ITK_VER=${ITK_VER}
 
 OPTIONS_DEFINE=	EXAMPLES TESTING
 EXAMPLES_DESC=	Build examples (very time consuming)
 TESTING_DESC=	Build testing programs (very time consuming)
 
 EXAMPLES_CMAKE_BOOL=	BUILD_EXAMPLES
 TESTING_CMAKE_BOOL=	BUILD_TESTING
 
 .include <bsd.port.pre.mk>
 
 .if ${CHOSEN_COMPILER_TYPE} == gcc
 PLIST_SUB+=	CHOSEN_COMPILER_TYPE="GNU"
 .else
 PLIST_SUB+=	CHOSEN_COMPILER_TYPE="Clang"
 .endif
 
 post-extract:
 	${MV} ${WRKDIR}/${PORTNAME}-${PORTVERSION}/.ExternalData/* ${WRKSRC}/.ExternalData/
 	${RM} -r ${WRKDIR}/${PORTNAME}-${PORTVERSION}
 
 .include <bsd.port.post.mk>