diff --git a/science/py-DendroPy/Makefile b/science/py-DendroPy/Makefile
index b53452c814d2..81b362750180 100644
--- a/science/py-DendroPy/Makefile
+++ b/science/py-DendroPy/Makefile
@@ -1,16 +1,20 @@
 PORTNAME=	DendroPy
-PORTVERSION=	4.6.1
+PORTVERSION=	5.0.0
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	wen@FreeBSD.org
 COMMENT=	Phylogenetic computing library
 WWW=		http://packages.python.org/DendroPy/
 
 LICENSE=	BSD3CLAUSE
 
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pip>0:devel/py-pip@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}pytest-runner>0:devel/py-pytest-runner@${PY_FLAVOR}
+
 USES=		python
 USE_PYTHON=	distutils autoplist
 
 .include <bsd.port.mk>
diff --git a/science/py-DendroPy/distinfo b/science/py-DendroPy/distinfo
index dd92d924dcca..180c65412e1c 100644
--- a/science/py-DendroPy/distinfo
+++ b/science/py-DendroPy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1686639965
-SHA256 (DendroPy-4.6.1.tar.gz) = 26fcbe1cb5831301e8f1f2e15a0563620f0b8e29e6d409dd6a2a7c957dd64c16
-SIZE (DendroPy-4.6.1.tar.gz) = 15200462
+TIMESTAMP = 1716853613
+SHA256 (DendroPy-5.0.0.tar.gz) = b6851e023cbee33b582ea4918427fd0395e77f0aef7e1fecb174e23be5b706ce
+SIZE (DendroPy-5.0.0.tar.gz) = 394460