diff --git a/biology/biosig/Makefile b/biology/biosig/Makefile
index 0cb338ebd382..7b8e5e2df212 100644
--- a/biology/biosig/Makefile
+++ b/biology/biosig/Makefile
@@ -1,36 +1,35 @@
 PORTNAME=	biosig
-DISTVERSION=	2.4.3
-PORTREVISION=	2
+DISTVERSION=	2.5.0
 CATEGORIES=	biology
 MASTER_SITES=	SF/${PORTNAME}/BioSig%20for%20C_C%2B%2B/src/
 DISTNAME=	${PORTNAME}-${PORTVERSION}.src
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Library for reading and writing different biosignal data format
 WWW=		http://biosig.sourceforge.net/
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 LIB_DEPENDS=	libb64.so:converters/libb64 \
 		libcholmod.so:math/suitesparse-cholmod \
 		libiconv.so:converters/libiconv \
 		libtinyxml.so:textproc/tinyxml
 
 USES=		gmake iconv localbase:ldflags tar:xz
 USE_LDCONFIG=	yes
 
 WRKSRC=		${WRKDIR}/${PORTNAME}-${DISTVERSION}
 
 GNU_CONFIGURE=	yes
 
 CFLAGS+=	-D__BYTE_ORDER=BYTE_ORDER -D__LITTLE_ENDIAN=LITTLE_ENDIAN -D__BIG_ENDIAN=BIG_ENDIAN \
 		-Dbswap_16=bswap16 -Dbswap_32=bswap32 -Dbswap_64=bswap64
 LDFLAGS+=	-liconv
 
 post-install:
 .for f in bin/biosig_fhir bin/biosig2gdf bin/physicalunits bin/save2gdf lib/libbiosig.so.3
 	@${STRIP_CMD} ${STAGEDIR}${PREFIX}/${f}
 .endfor
 
 .include <bsd.port.mk>
diff --git a/biology/biosig/distinfo b/biology/biosig/distinfo
index 78ac6460e9c3..2525118c8bc2 100644
--- a/biology/biosig/distinfo
+++ b/biology/biosig/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1665337308
-SHA256 (biosig-2.4.3.src.tar.xz) = 7b6000e2275c00a67d7a25aaf7ffad229978d124315f5f910844b33a8a61e532
-SIZE (biosig-2.4.3.src.tar.xz) = 1867672
+TIMESTAMP = 1672383148
+SHA256 (biosig-2.5.0.src.tar.xz) = 25ffaf0ee906904e6af784f33ed1ad8ad55280e40bc9dac07a487833ebd124d0
+SIZE (biosig-2.5.0.src.tar.xz) = 1895956
diff --git a/biology/biosig/files/patch-Makefile.in b/biology/biosig/files/patch-Makefile.in
new file mode 100644
index 000000000000..f10025ef16ee
--- /dev/null
+++ b/biology/biosig/files/patch-Makefile.in
@@ -0,0 +1,49 @@
+--- Makefile.in.orig	2022-12-30 07:04:03 UTC
++++ Makefile.in
+@@ -11,7 +11,7 @@ exec_prefix ?= $(prefix)
+ first :: lib tools
+ 
+ java: lib
+-	$(MAKE) -C biosig4c++/java
++	#$(MAKE) -C biosig4c++/java
+ 
+ lib:
+ 	$(MAKE) -C biosig4c++ lib
+@@ -52,8 +52,8 @@ distclean : clean
+ 		biosig4c++/python/setup.py \
+ 		biosig4c++/R/DESCRIPTION
+ 
+-ifneq (:,@JAVA@)
+-ifneq (:,@JAVAC@)
++ifneq (:,:)
++ifneq (:,:)
+ first :: lib
+ 	-$(MAKE) -C biosig4c++/java
+ endif
+@@ -91,7 +91,7 @@ biosig4octave ::
+ 	$(MAKE) -C biosig4c++ biosig4octave
+ 	ln -sf biosig4c++/mex/biosig4octave-@PACKAGE_VERSION@.src.tar.gz
+ 
+-ifneq (:,@OCTAVE@)
++ifneq (:,:)
+ ifneq (:,@MKOCTFILE@)
+ BIOSIG_MEX_DIR = $(DESTDIR)$(shell octave-config -p LOCALOCTFILEDIR)/biosig
+ BIOSIG_DIR     = $(DESTDIR)$(shell octave-config -p LOCALFCNFILEDIR)/biosig
+@@ -127,7 +127,7 @@ clean ::
+ 	-$(MAKE) -C biosig4c++/php clean
+ endif
+ 
+-ifneq (:,@PYTHON3@)
++ifneq (:,:)
+ first :: python
+ python ::
+ 	-PYTHON=@PYTHON3@ $(MAKE) -C biosig4c++/python sdist
+@@ -145,7 +145,7 @@ clean ::
+ 	$(MAKE) -C biosig4c++/python clean
+ endif
+ 
+-ifneq (:,@R@)
++ifneq (:,:)
+ first ::
+ 	-$(MAKE) -C biosig4c++/R build
+ install ::