diff --git a/science/py-GPy/Makefile b/science/py-GPy/Makefile
index 68cb7fd123b8..b128352a3649 100644
--- a/science/py-GPy/Makefile
+++ b/science/py-GPy/Makefile
@@ -1,23 +1,22 @@
 PORTNAME=	GPy
-DISTVERSION=	1.9.9
-PORTREVISION=	1
+DISTVERSION=	1.10.0
 CATEGORIES=	science python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Gaussian process toolbox
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
 BUILD_DEPENDS=	${PYNUMPY}
 RUN_DEPENDS=	${PYNUMPY} \
-		${PYTHON_PKGNAMEPREFIX}scipy>=0.16:science/py-scipy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}scipy>=1.3.0:science/py-scipy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}six>0:devel/py-six@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}paramz>=0.9.0:science/py-paramz@${PY_FLAVOR}
 
 USES=		localbase python:3.6+
 USE_PYTHON=	distutils autoplist
 
 .include <bsd.port.mk>
diff --git a/science/py-GPy/distinfo b/science/py-GPy/distinfo
index c3d01436181b..1ff3a937881b 100644
--- a/science/py-GPy/distinfo
+++ b/science/py-GPy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1571531871
-SHA256 (GPy-1.9.9.tar.gz) = 04faf0c24eacc4dea60727c50a48a07ddf9b5751a3b73c382105e2a31657c7ed
-SIZE (GPy-1.9.9.tar.gz) = 995060
+TIMESTAMP = 1621666653
+SHA256 (GPy-1.10.0.tar.gz) = a2b793ef8d0ac71739e7ba1c203bc8a5afa191058b42caa617e0e29aa52aa6fb
+SIZE (GPy-1.10.0.tar.gz) = 959398