diff --git a/biology/py-mrcfile/Makefile b/biology/py-mrcfile/Makefile
index 9ad5ea1a08b5..a5e98434bf38 100644
--- a/biology/py-mrcfile/Makefile
+++ b/biology/py-mrcfile/Makefile
@@ -1,21 +1,21 @@
 PORTNAME=	mrcfile
-DISTVERSION=	1.4.2
+DISTVERSION=	1.4.3
 CATEGORIES=	biology python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	MRC file I/O library which is used in structural biology
 WWW=		https://github.com/ccpem/mrcfile
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
 RUN_DEPENDS=	${PYNUMPY}
 
 USES=		python
 USE_PYTHON=	distutils concurrent autoplist
 
 NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/biology/py-mrcfile/distinfo b/biology/py-mrcfile/distinfo
index 78e67a14d1fb..2105f7e6a05b 100644
--- a/biology/py-mrcfile/distinfo
+++ b/biology/py-mrcfile/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1659083351
-SHA256 (mrcfile-1.4.2.tar.gz) = 447022f27b7ce4bf57f97010f092a811ce88635479de7f8a86449a0c9cb319fe
-SIZE (mrcfile-1.4.2.tar.gz) = 34702
+TIMESTAMP = 1664056297
+SHA256 (mrcfile-1.4.3.tar.gz) = 43c358c59ff8f583fc4dc2079a0099028719109ebf92066e388772bab389c5f5
+SIZE (mrcfile-1.4.3.tar.gz) = 35831