diff --git a/science/py-MDAnalysisTests/Makefile b/science/py-MDAnalysisTests/Makefile
index d29cf5c94e6e..df63e224953b 100644
--- a/science/py-MDAnalysisTests/Makefile
+++ b/science/py-MDAnalysisTests/Makefile
@@ -1,23 +1,27 @@
 PORTNAME=	MDAnalysisTests
-DISTVERSION=	2.7.0
-PORTREVISION=	3
+DISTVERSION=	2.10.0
 CATEGORIES=	science python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Test code and the trajectory data for test cases of MDAnalysis
 WWW=		https://www.mdanalysis.org
 
 LICENSE=	GPLv2
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy1>=1.16:math/py-numpy1@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}MDAnalysis>0:science/py-MDAnalysis@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hypothesis>0:devel/py-hypothesis@${PY_FLAVOR}
+TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}hypothesis>0:devel/py-hypothesis@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	distutils autoplist pytest
 NO_ARCH=	yes
 
+WRKSRC=		${WRKDIR}/mdanalysistests-${DISTVERSION}
+
+# tests as of 2.10.0
+
 .include <bsd.port.mk>
diff --git a/science/py-MDAnalysisTests/distinfo b/science/py-MDAnalysisTests/distinfo
index f39c637c7f98..fbbb381eca33 100644
--- a/science/py-MDAnalysisTests/distinfo
+++ b/science/py-MDAnalysisTests/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1715029181
-SHA256 (MDAnalysisTests-2.7.0.tar.gz) = 326d65d7f14da8d1b047aab87ca312a68459a5fd18ddf6d8cb9ac9c3ca51d9e5
-SIZE (MDAnalysisTests-2.7.0.tar.gz) = 55704756
+TIMESTAMP = 1777493576
+SHA256 (MDAnalysisTests-2.10.0.tar.gz) = 286b8678e19195093a19b57b26d76b8274415d33ac23fc872355639fcb49beef
+SIZE (MDAnalysisTests-2.10.0.tar.gz) = 57933275
diff --git a/science/py-MDAnalysisTests/files/patch-MDAnalysisTests_transformations_test__base.py b/science/py-MDAnalysisTests/files/patch-MDAnalysisTests_transformations_test__base.py
index 02b82d1edb7e..4dfaa1f28897 100644
--- a/science/py-MDAnalysisTests/files/patch-MDAnalysisTests_transformations_test__base.py
+++ b/science/py-MDAnalysisTests/files/patch-MDAnalysisTests_transformations_test__base.py
@@ -1,54 +1,33 @@
---- MDAnalysisTests/transformations/test_base.py.orig	2022-06-02 18:49:13 UTC
+-- threadpoolctl is not available/functional on FreeBSD.
+-- This patch comments out threadpoolctl import and usage to allow the package
+-- to build and run on FreeBSD.
+---
+--- MDAnalysisTests/transformations/test_base.py.orig	2026-04-29 20:16:20 UTC
 +++ MDAnalysisTests/transformations/test_base.py
-@@ -23,7 +23,8 @@ from numpy.testing import assert_equal
+@@ -22,7 +22,8 @@ from numpy.testing import assert_equal
  import numpy as np
  import pytest
  from numpy.testing import assert_equal
 -from threadpoolctl import threadpool_info
 +# threadpoolctl is not yet usable on FreeBSD
 +#from threadpoolctl import threadpool_info
  
  import MDAnalysis as mda
  from MDAnalysisTests.datafiles import PSF, DCD
 @@ -36,7 +37,7 @@ class DefaultTransformation(TransformationBase):
          super().__init__()
  
      def _transform(self, ts):
 -        self.runtime_info = threadpool_info()
 +        """self.runtime_info = threadpool_info()"""
          ts.positions = ts.positions + 1
          return ts
  
-@@ -54,7 +55,7 @@ class CustomTransformation(TransformationBase):
-                          parallelizable=parallelizable)
+@@ -57,7 +58,7 @@ class CustomTransformation(TransformationBase):
+         )
  
      def _transform(self, ts):
 -        self.runtime_info = threadpool_info()
 +        """self.runtime_info = threadpool_info()"""
          ts.positions = ts.positions + 1
          return ts
- 
-@@ -88,17 +89,17 @@ def test_thread_limit_apply(u):
- 
- 
- def test_thread_limit_apply(u):
--    default_thread_info = threadpool_info()
-+    """default_thread_info = threadpool_info()
-     default_num_thread_limit_list = [thread_info['num_threads']
-                                      for thread_info in default_thread_info]
- 
-     new_trans = CustomTransformation(max_threads=2)
-     _ = new_trans(u.trajectory.ts)
--    for thread_info in new_trans.runtime_info:
--        assert thread_info['num_threads'] == 2
-+    for thread_info in new_trans.runtime_info:"""
-+    assert thread_info['num_threads'] == 2
- 
-     #  test the thread limit is only applied locally.
--    new_thread_info = threadpool_info()
-+    """new_thread_info = threadpool_info()
-     new_num_thread_limit_list = [thread_info['num_threads']
--                                 for thread_info in new_thread_info]
--    assert_equal(default_num_thread_limit_list, new_num_thread_limit_list)
-+                                 for thread_info in new_thread_info]"""
-+    assert_equal(default_num_thread_limit_list, 2)
diff --git a/science/py-MDAnalysisTests/pkg-descr b/science/py-MDAnalysisTests/pkg-descr
index ade8e8a2faf0..4242bfbbab4c 100644
--- a/science/py-MDAnalysisTests/pkg-descr
+++ b/science/py-MDAnalysisTests/pkg-descr
@@ -1 +1,4 @@
-Test code and data for science/py-MDAnalysis.
+Test code and trajectory data for the test cases of MDAnalysis.
+
+This package provides the test suite and test data files required to run the
+full test suite of MDAnalysis.