diff --git a/misc/py-sagemaker-serve/Makefile b/misc/py-sagemaker-serve/Makefile
index 3829dbfbabff..9e5e989039a0 100644
--- a/misc/py-sagemaker-serve/Makefile
+++ b/misc/py-sagemaker-serve/Makefile
@@ -1,50 +1,50 @@
 PORTNAME=	sagemaker-serve
-DISTVERSION=	1.17.0
+DISTVERSION=	1.21.0
 CATEGORIES=	misc python # machine-learning
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DISTNAME=	${PORTNAME:S/-/_/}-${PORTVERSION}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	SageMaker: Library for training & deploying models on Amazon SageMaker
 WWW=		https://sagemaker.readthedocs.io/en/stable/ \
 		https://github.com/aws/sagemaker-python-sdk
 
 LICENSE=	APACHE20
 
 BUILD_DEPENDS=	${PY_SETUPTOOLS} \
 		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}boto3>=1.42.2,<2.0:www/py-boto3@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}botocore>=1.35.75,<2.0:devel/py-botocore@${PY_FLAVOR} \
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}boto3>=1.42.2:www/py-boto3@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}botocore>=1.35.75:devel/py-botocore@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}deepdiff>0:devel/py-deepdiff@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}mlflow-skinny>0:misc/py-mlflow-skinny@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}onnx>0:misc/py-onnx@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}onnxruntime>0:misc/py-onnxruntime@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}psutil>=0:sysutils/py-psutil@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest>0:devel/py-pytest@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytorch>=2.0.0:misc/py-pytorch@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}sagemaker-core>=2.17.0:misc/py-sagemaker-core@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}sagemaker-core>=2.21.0:misc/py-sagemaker-core@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}sagemaker-schema-inference-artifacts>=0:misc/py-sagemaker-schema-inference-artifacts@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}sagemaker-train>=1.17.0:misc/py-sagemaker-train@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}sagemaker-train>=1.21.0:misc/py-sagemaker-train@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tqdm>0:misc/py-tqdm@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tritonclient>0:misc/py-tritonclient@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	pep517 autoplist
 
 NO_ARCH=	yes
 
 post-stage:
 	@${RM} ${STAGEDIR}${PYTHON_SITELIBDIR}/sagemaker/__init__.py
 	@${RM} ${STAGEDIR}${PYTHON_SITELIBDIR}/sagemaker/__pycache__/__init__*.pyc
 	@${RMDIR} ${STAGEDIR}${PYTHON_SITELIBDIR}/sagemaker/__pycache__ 2>/dev/null || true
 
 POST_PLIST=	fix-plist
 
 fix-plist:
 	@${REINPLACE_CMD} -e '/sagemaker\/__init__/d' ${TMPPLIST}
 	@${REINPLACE_CMD} -e '/sagemaker\/__pycache__/d' ${TMPPLIST}
 
-# tests as of 1.17.0: no tests defined
+# tests as of 1.21.0: no tests defined
 
 .include <bsd.port.mk>
diff --git a/misc/py-sagemaker-serve/distinfo b/misc/py-sagemaker-serve/distinfo
index 5f97c1b78643..81c0c23c680c 100644
--- a/misc/py-sagemaker-serve/distinfo
+++ b/misc/py-sagemaker-serve/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1784963036
-SHA256 (sagemaker_serve-1.17.0.tar.gz) = 9ada8a292b33c3b590c6d3d342770edf4b294a6b5ef9946306a19f651972b56f
-SIZE (sagemaker_serve-1.17.0.tar.gz) = 212650
+TIMESTAMP = 1789072351
+SHA256 (sagemaker_serve-1.21.0.tar.gz) = 36895d4b0f866a7a546de921f097d56b626adab14da227c2a1c9063e0d560d02
+SIZE (sagemaker_serve-1.21.0.tar.gz) = 241771