diff --git a/devel/py-qutip/Makefile b/devel/py-qutip/Makefile
index 27c68b6f8ec7..e2453835d0d2 100644
--- a/devel/py-qutip/Makefile
+++ b/devel/py-qutip/Makefile
@@ -1,39 +1,36 @@
 PORTNAME=	qutip
-DISTVERSION=	5.3.0
+DISTVERSION=	5.3.1
 CATEGORIES=	devel
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Quantum toolbox in python
 WWW=		https://qutip.org/
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
-PY_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.16:math/py-numpy@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}matplotlib>0:math/py-matplotlib@${PY_FLAVOR} \
+BUILD_DEPENDS=	${PY_SETUPTOOLS} \
+		${PYTHON_PKGNAMEPREFIX}numpy>=2.0.0:math/py-numpy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}packaging>0:devel/py-packaging@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}scipy>=1.9:science/py-scipy@${PY_FLAVOR}
-BUILD_DEPENDS=	${PY_DEPENDS} \
-		${PY_SETUPTOOLS} \
-		${PYTHON_PKGNAMEPREFIX}pip>0:devel/py-pip@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}wheel>=0.32.0:devel/py-wheel@${PY_FLAVOR}
-RUN_DEPENDS=	${PY_DEPENDS}
-TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}nose>0:devel/py-nose@${PY_FLAVOR}
-# the optional graphics/py-mayavi dependency is omitted because it is python-2.7 -only
+		${PYTHON_PKGNAMEPREFIX}scipy>=1.9:science/py-scipy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>=1.23.2:math/py-numpy@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}packaging>0:devel/py-packaging@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}scipy>=1.9.2:science/py-scipy@${PY_FLAVOR}
+RUN_DEPENDS+=	${PYTHON_PKGNAMEPREFIX}matplotlib>0:math/py-matplotlib@${PY_FLAVOR}
+TEST_DEPENDS=	# tests need missing loky, and many optional dependencies, need extra work
 
 USES=		python
 USE_PYTHON=	autoplist cython cython_run pep517
 
-post-install:
-	@${STRIP_CMD} \
-		${STAGEDIR}${PYTHON_SITELIBDIR}/qutip/*/*${PYTHON_TAG}.so \
-		${STAGEDIR}${PYTHON_SITELIBDIR}/qutip/*/*/*${PYTHON_TAG}.so
+TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHON_SITELIBDIR}
+TEST_ARGS=	--disable-plugin-autoload
 
-do-test: # 3 tests fail, see https://github.com/qutip/qutip/issues/2190
+do-test: # tests have missing deps, need more work
 	@${ECHO} "==> Running tests. Please note that tests require X11 display access."
 	@cd ${WRKDIR} && ${SETENV} ${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHON_SITELIBDIR} \
 		${PYTHON_CMD} -c "import qutip.testing as qt; qt.run();"
 
 .include <bsd.port.mk>
diff --git a/devel/py-qutip/distinfo b/devel/py-qutip/distinfo
index d6bfa2671b33..1d20354ce58d 100644
--- a/devel/py-qutip/distinfo
+++ b/devel/py-qutip/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1779741217
-SHA256 (qutip-5.3.0.tar.gz) = ab782e4c8e38c0d5d4221f2ffe4d8fc6887f83e039b3e5776e87dfbb1deee1c3
-SIZE (qutip-5.3.0.tar.gz) = 6897149
+TIMESTAMP = 1790136104
+SHA256 (qutip-5.3.1.tar.gz) = 056206b40cbe97c3c7e4f85eff11873406669cd72b2db039fa1a3812767395e9
+SIZE (qutip-5.3.1.tar.gz) = 6931453