diff --git a/biology/wfa2-lib/Makefile b/biology/wfa2-lib/Makefile
index cb334b9bf0c3..2300f379ec6f 100644
--- a/biology/wfa2-lib/Makefile
+++ b/biology/wfa2-lib/Makefile
@@ -1,20 +1,21 @@
 PORTNAME=		wfa2-lib
 DISTVERSIONPREFIX=	v
 DISTVERSION=		2.3.2
+PORTREVISION=		1
 CATEGORIES=		biology
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Exact gap-affine algorithm using homology to accelerate alignment
 WWW=		https://github.com/smarco/WFA2-lib
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 USES=		cmake pkgconfig
 USE_GITHUB=	yes
 USE_LDCONFIG=	yes
 
 GH_ACCOUNT=	smarco
 GH_PROJECT=	WFA2-lib
 
 .include <bsd.port.mk>
diff --git a/biology/wfa2-lib/files/patch-CMakeLists.txt b/biology/wfa2-lib/files/patch-CMakeLists.txt
new file mode 100644
index 000000000000..8b71ad656f0a
--- /dev/null
+++ b/biology/wfa2-lib/files/patch-CMakeLists.txt
@@ -0,0 +1,11 @@
+--- CMakeLists.txt.orig	2023-01-31 15:02:27 UTC
++++ CMakeLists.txt
+@@ -55,7 +55,7 @@ if(NOT CMAKE_BUILD_TYPE)
+ endif()
+ 
+ if (${CMAKE_BUILD_TYPE} MATCHES Release)
+-  set(OPTIMIZE_FLAGS "${OPTIMIZE_FLAGS} -march=native -D_FILE_OFFSET_BITS=64")
++  set(OPTIMIZE_FLAGS "${OPTIMIZE_FLAGS} -D_FILE_OFFSET_BITS=64")
+ endif()
+ 
+ if ((${CMAKE_BUILD_TYPE} MATCHES Release) OR (${CMAKE_BUILD_TYPE} MATCHES RelWithDebInfo))