diff --git a/science/thermofun/Makefile b/science/thermofun/Makefile
index bcf9bacbf96c..16573bf51c04 100644
--- a/science/thermofun/Makefile
+++ b/science/thermofun/Makefile
@@ -1,40 +1,41 @@
 PORTNAME=	thermofun
 DISTVERSIONPREFIX=	v
-DISTVERSION=	0.4.0
+DISTVERSION=	0.4.1
 CATEGORIES=	science # chemistry
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Code for calculating thermodynamic properties of materials
 WWW=		https://github.com/thermohub/thermofun
 
 LICENSE=	LGPL3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 BUILD_DEPENDS=	nlohmann-json>0:devel/nlohmann-json \
 		spdlog>0:devel/spdlog
 LIB_DEPENDS=	libChemicalFun.so:science/chemicalfun
 
 USES=		cmake compiler:c++14-lang
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	thermohub
 
 CXXFLAGS+=	-DSPDLOG_FMT_EXTERNAL # see https://bugs.freebsd.org/bugzilla/show_bug.cgi?id=258073#c3
 
 TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 TEST_WRKSRC=	${WRKSRC}
 
 OPTIONS_DEFINE=		PYTHON
 OPTIONS_DEFAULT=	PYTHON
 OPTIONS_SUB=		yes
 
 PYTHON_USES=		python
-PYTHON_USE=		PYTHON=pytest # 2 tests fail, see https://github.com/thermohub/thermofun/issues/37
+PYTHON_USE=		PYTHON=pytest
 PYTHON_CMAKE_BOOL=	TFUN_BUILD_PYTHON
 PYTHON_CMAKE_ON=	-DFREEBSD_STAGEDIR=${STAGEDIR}
-PYTHON_BUILD_DEPENDS=	pybind11>0:devel/pybind11
+PYTHON_BUILD_DEPENDS=	pybind11>0:devel/pybind11 \
+			${PYTHON_PKGNAMEPREFIX}setuptools>0:devel/py-setuptools@${PY_FLAVOR}
 
 post-install-PYTHON-on:
 	@${STRIP_CMD} ${STAGEDIR}${PYTHON_SITELIBDIR}/thermofun/PyThermoFun${PYTHON_EXT_SUFFIX}.so
 
 .include <bsd.port.mk>
diff --git a/science/thermofun/distinfo b/science/thermofun/distinfo
index 6271051840cf..add6b515ddbb 100644
--- a/science/thermofun/distinfo
+++ b/science/thermofun/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1658079403
-SHA256 (thermohub-thermofun-v0.4.0_GH0.tar.gz) = bd863174a272ddf166643312bc4b759cb429ed0230e9023678357673e56569b2
-SIZE (thermohub-thermofun-v0.4.0_GH0.tar.gz) = 1340065
+TIMESTAMP = 1669583901
+SHA256 (thermohub-thermofun-v0.4.1_GH0.tar.gz) = 4f0cf27876a18e9be1c0d882b1ec0a031c41c29d6b6cb541f058ea9be958c2a0
+SIZE (thermohub-thermofun-v0.4.1_GH0.tar.gz) = 1341676
diff --git a/science/thermofun/pkg-plist b/science/thermofun/pkg-plist
index ae0bee96a6b6..ec205216f226 100644
--- a/science/thermofun/pkg-plist
+++ b/science/thermofun/pkg-plist
@@ -1,74 +1,77 @@
 include/ThermoFun/Batch/OutputBatch.h
 include/ThermoFun/Batch/ThermoBatch.h
 include/ThermoFun/Common/Exception.h
 include/ThermoFun/Common/OutputToCSV.h
 include/ThermoFun/Common/OutputWaterSteamConventionProp.h
 include/ThermoFun/Common/ParseJsonToData.h
 include/ThermoFun/Common/ScalarTypes.hpp
 include/ThermoFun/Common/ThermoOmp.h
 include/ThermoFun/Common/ThermoScalar.hpp
 include/ThermoFun/Common/Units.hpp
 include/ThermoFun/Database.h
 include/ThermoFun/ElectroModelsSolvent.h
 include/ThermoFun/Element.h
 include/ThermoFun/GlobalVariables.h
 include/ThermoFun/OptimizationUtils.h
 include/ThermoFun/Reaction.h
 include/ThermoFun/Reactions/DolejsManning2010.h
 include/ThermoFun/Reactions/FrantzMarshall.h
 include/ThermoFun/Reactions/LogK_function_of_T.h
 include/ThermoFun/Reactions/RyzhenkoBryzgalyn.h
 include/ThermoFun/Reactions/Volume_function_of_T.h
 include/ThermoFun/Substance.h
 include/ThermoFun/Substances/EmpiricalCpIntegration.h
 include/ThermoFun/Substances/Gases/GasCGF.h
 include/ThermoFun/Substances/Gases/GasCORK.h
 include/ThermoFun/Substances/Gases/GasPR78.h
 include/ThermoFun/Substances/Gases/GasPRSV.h
 include/ThermoFun/Substances/Gases/GasSRK.h
 include/ThermoFun/Substances/Gases/GasSTP.h
 include/ThermoFun/Substances/Gases/s_solmod_.h
 include/ThermoFun/Substances/Gases/verror.h
 include/ThermoFun/Substances/Solids/SolidBMGottschalk.h
 include/ThermoFun/Substances/Solids/SolidBerman88.h
 include/ThermoFun/Substances/Solids/SolidHPLandau.h
 include/ThermoFun/Substances/Solids/SolidMurnaghanHP98.h
 include/ThermoFun/Substances/Solute/SoluteADgems.h
 include/ThermoFun/Substances/Solute/SoluteAnderson91.h
 include/ThermoFun/Substances/Solute/SoluteHKFgems.h
 include/ThermoFun/Substances/Solute/SoluteHKFreaktoro.h
 include/ThermoFun/Substances/Solute/SoluteHollandPowell98.h
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterConstants.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterElectroState.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterElectroStateJohnsonNorton.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterHelmholtzState.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterHelmholtzStateHGK.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterHelmholtzStateWagnerPruss.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterThermoState.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterThermoStateUtils.hpp
 include/ThermoFun/Substances/Solvent/Reaktoro/WaterUtils.hpp
 include/ThermoFun/Substances/Solvent/WaterElectroFernandez1997.h
 include/ThermoFun/Substances/Solvent/WaterElectroSverjensky2014.h
 include/ThermoFun/Substances/Solvent/WaterHGK-JNgems.h
 include/ThermoFun/Substances/Solvent/WaterHGKreaktoro.h
 include/ThermoFun/Substances/Solvent/WaterIdealGasWolley.h
 include/ThermoFun/Substances/Solvent/WaterJN91reaktoro.h
 include/ThermoFun/Substances/Solvent/WaterWP95reaktoro.h
 include/ThermoFun/Substances/Solvent/WaterZhangDuan2005.h
 include/ThermoFun/Substances/StandardEntropyCpIntegration.h
 include/ThermoFun/ThermoEngine.h
 include/ThermoFun/ThermoFun.h
 include/ThermoFun/ThermoModelsReaction.h
 include/ThermoFun/ThermoModelsSolvent.h
 include/ThermoFun/ThermoModelsSubstance.h
 include/ThermoFun/ThermoParameters.h
 include/ThermoFun/ThermoProperties.h
 lib/cmake/ThermoFun/ThermoFunConfig.cmake
 lib/cmake/ThermoFun/ThermoFunConfigVersion.cmake
 lib/cmake/ThermoFun/ThermoFunTargets-%%CMAKE_BUILD_TYPE%%.cmake
 lib/cmake/ThermoFun/ThermoFunTargets.cmake
 lib/libThermoFun.so
+%%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun-0.4.1-py%%PYTHON_VER%%.egg-info/PKG-INFO
+%%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun-0.4.1-py%%PYTHON_VER%%.egg-info/SOURCES.txt
+%%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun-0.4.1-py%%PYTHON_VER%%.egg-info/dependency_links.txt
+%%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun-0.4.1-py%%PYTHON_VER%%.egg-info/top_level.txt
 %%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun/PyThermoFun%%PYTHON_EXT_SUFFIX%%.so
 %%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun/__init__.py
 %%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun/__pycache__/__init__%%PYTHON_EXT_SUFFIX%%.pyc
-%%PYTHON%%%%PYTHON_SITELIBDIR%%/thermofun-0.4.0-py%%PYTHON_VER%%.egg-info