diff --git a/archivers/c-blosc2/Makefile b/archivers/c-blosc2/Makefile
index 8472bf185f66..896c37f1120c 100644
--- a/archivers/c-blosc2/Makefile
+++ b/archivers/c-blosc2/Makefile
@@ -1,39 +1,38 @@
 # Created by: Po-Chuan Hsieh <sunpoet@FreeBSD.org>
 
 PORTNAME=	c-blosc2
-PORTVERSION=	2.0.4
-PORTREVISION=	1
+PORTVERSION=	2.1.0
 DISTVERSIONPREFIX=	v
 CATEGORIES=	archivers
 
 MAINTAINER=	sunpoet@FreeBSD.org
 COMMENT=	High performance compressor optimized for binary data
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
 LIB_DEPENDS=	liblz4.so:archivers/liblz4 \
 		libzstd.so:archivers/zstd
 
 USES=		cmake
 
 CMAKE_OFF=	BUILD_LITE DEACTIVATE_AVX2 DEACTIVATE_ZLIB DEACTIVATE_ZSTD
 CMAKE_ON=	BUILD_BENCHMARKS BUILD_EXAMPLES BUILD_FUZZERS BUILD_PLUGINS BUILD_SHARED BUILD_STATIC BUILD_TESTS DEACTIVATE_IPP PREFER_EXTERNAL_LZ4 PREFER_EXTERNAL_ZLIB PREFER_EXTERNAL_ZSTD TEST_INCLUDE_COMPAT TEST_INCLUDE_EXAMPLES
 USE_LDCONFIG=	yes
 
 PLIST_SUB=	PORTVERSION=${PORTVERSION}
 
 GH_ACCOUNT=	Blosc
 USE_GITHUB=	yes
 
 .include <bsd.port.options.mk>
 
 .if ${ARCH} == powerpc64le
 USES+=		compiler:gcc-c++11-lib
 USE_CSTD=	c11
 .endif
 
 do-test:
 	cd ${TEST_WRKSRC} && ctest
 
 .include <bsd.port.mk>
diff --git a/archivers/c-blosc2/distinfo b/archivers/c-blosc2/distinfo
index 4f622a26dcf2..341a1553f791 100644
--- a/archivers/c-blosc2/distinfo
+++ b/archivers/c-blosc2/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1635730865
-SHA256 (Blosc-c-blosc2-v2.0.4_GH0.tar.gz) = 90c78edcc262759dd16d243141513310624bb4fda3d98ac34dcfb78255e151c1
-SIZE (Blosc-c-blosc2-v2.0.4_GH0.tar.gz) = 2062503
+TIMESTAMP = 1650228660
+SHA256 (Blosc-c-blosc2-v2.1.0_GH0.tar.gz) = a9570f4101654c2fe2a706adcab0821cdbcf7523fcb6602407dda21b67fdacfd
+SIZE (Blosc-c-blosc2-v2.1.0_GH0.tar.gz) = 2345202
diff --git a/archivers/c-blosc2/files/patch-CMakeLists.txt b/archivers/c-blosc2/files/patch-CMakeLists.txt
deleted file mode 100644
index 225e7f49f0ce..000000000000
--- a/archivers/c-blosc2/files/patch-CMakeLists.txt
+++ /dev/null
@@ -1,11 +0,0 @@
---- CMakeLists.txt.orig	2021-11-02 17:39:13 UTC
-+++ CMakeLists.txt
-@@ -303,7 +303,7 @@ elseif(CMAKE_SYSTEM_PROCESSOR STREQUAL armv7l OR
-         # Unrecognized compiler. Emit a warning message to let the user know hardware-acceleration won't be available.
-         message(WARNING "Unable to determine which ${CMAKE_SYSTEM_PROCESSOR} hardware features are supported by the C compiler (${CMAKE_C_COMPILER_ID} ${CMAKE_C_COMPILER_VERSION}).")
-     endif()
--elseif(CMAKE_SYSTEM_PROCESSOR STREQUAL ppc64le)
-+elseif(CMAKE_SYSTEM_PROCESSOR MATCHES "^(ppc64le|powerpc64le)")
-     if(CMAKE_C_COMPILER_ID STREQUAL GNU AND CMAKE_C_COMPILER_VERSION VERSION_GREATER 8)
-         set(COMPILER_SUPPORT_ALTIVEC TRUE)
-     else()