diff --git a/science/py-pydicom/Makefile b/science/py-pydicom/Makefile
index cbc906fee7e8..00bda444d5c0 100644
--- a/science/py-pydicom/Makefile
+++ b/science/py-pydicom/Makefile
@@ -1,18 +1,18 @@
 PORTNAME=	pydicom
-PORTVERSION=	2.4.2
+PORTVERSION=	2.4.3
 DISTVERSIONPREFIX=v
 CATEGORIES=	science python
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	wen@FreeBSD.org
 COMMENT=	Read, modify, and write DICOM files with Python code
 WWW=		https://github.com/pydicom/pydicom
 
 LICENSE=	MIT
 
 USES=		python shebangfix
 USE_GITHUB=	yes
 USE_PYTHON=	distutils autoplist
 NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/science/py-pydicom/distinfo b/science/py-pydicom/distinfo
index 0c7b8f701ec5..25e96492136d 100644
--- a/science/py-pydicom/distinfo
+++ b/science/py-pydicom/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1690670604
-SHA256 (pydicom-pydicom-v2.4.2_GH0.tar.gz) = c79c01fdeddb8cf11a7a304944d2ba28f331a3a08ca679e0826a303a98ec400f
-SIZE (pydicom-pydicom-v2.4.2_GH0.tar.gz) = 2202646
+TIMESTAMP = 1692276397
+SHA256 (pydicom-pydicom-v2.4.3_GH0.tar.gz) = ffb8d729fcaacf7a3aca243c69fa342305d2696ec59c1f930b2e564d4f1b5fbd
+SIZE (pydicom-pydicom-v2.4.3_GH0.tar.gz) = 2202653