diff --git a/biology/hyphy/Makefile b/biology/hyphy/Makefile
index 80ae747bc589..c56703283a9e 100644
--- a/biology/hyphy/Makefile
+++ b/biology/hyphy/Makefile
@@ -1,24 +1,24 @@
 PORTNAME=	hyphy
-DISTVERSION=	2.5.38
+DISTVERSION=	2.5.39
 CATEGORIES=	biology
 
 MAINTAINER=	jrm@FreeBSD.org
 COMMENT=	Hypothesis testing using Phylogenies
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 ONLY_FOR_ARCHS=	aarch64 amd64 armv7 i386 powerpc64le powerpc64 powerpc
 
 LIB_DEPENDS=	libcurl.so:ftp/curl
 
 USES=		cmake localbase:ldflags
 USE_GITHUB=	yes
 GH_ACCOUNT=	veg
 
 OPTIONS_DEFINE=	AVX
 AVX_DESC=	Advanced vector extensions support
 
 AVX_CMAKE_OFF=	-DNOAVX:BOOL=ON
 
 .include <bsd.port.mk>
diff --git a/biology/hyphy/distinfo b/biology/hyphy/distinfo
index 0e642ff3cb29..fb5a444fb4a3 100644
--- a/biology/hyphy/distinfo
+++ b/biology/hyphy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1650376110
-SHA256 (veg-hyphy-2.5.38_GH0.tar.gz) = 1b66af17f9f7dd0e9951a9bd3b106b95bf5915a78523973ba79af64f970770d6
-SIZE (veg-hyphy-2.5.38_GH0.tar.gz) = 5365153
+TIMESTAMP = 1653616548
+SHA256 (veg-hyphy-2.5.39_GH0.tar.gz) = b2382dc95924ddea09fc1a795568d5727c4b0bdee916f1f41afc6401363f0cf5
+SIZE (veg-hyphy-2.5.39_GH0.tar.gz) = 5374983