diff --git a/biology/py-dna-features-viewer/Makefile b/biology/py-dna-features-viewer/Makefile
index ebfa72d4bdb7..2e75580db9af 100644
--- a/biology/py-dna-features-viewer/Makefile
+++ b/biology/py-dna-features-viewer/Makefile
@@ -1,24 +1,27 @@
 PORTNAME=	dna-features-viewer
-DISTVERSION=	3.1.3
-PORTREVISION=	2
+DISTVERSION=	3.1.5
 CATEGORIES=	biology python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 DISTNAME=	dna_features_viewer-${PORTVERSION}
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Python library to visualize DNA features, e.g. GenBank or Gff files
 WWW=		https://github.com/Edinburgh-Genome-Foundry/DnaFeaturesViewer
 
 LICENSE=	MIT
-LICENSE_FILE=	${WRKSRC}/LICENCE.txt
+LICENSE_FILE=	${WRKSRC}/LICENSE
 
+BUILD_DEPENDS=	${PY_SETUPTOOLS} \
+		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}matplotlib>=3:math/py-matplotlib@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}bcbio-gff>0:biology/py-bcbio-gff@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}packaging>0:devel/py-packaging@${PY_FLAVOR}
 
 USES=		python
-USE_PYTHON=	autoplist distutils
+USE_PYTHON=	autoplist pep517
+
+NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/biology/py-dna-features-viewer/distinfo b/biology/py-dna-features-viewer/distinfo
index 18a670d041ec..3a77e5f54740 100644
--- a/biology/py-dna-features-viewer/distinfo
+++ b/biology/py-dna-features-viewer/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1698839049
-SHA256 (dna_features_viewer-3.1.3.tar.gz) = 7af179ab1b3c0dedd09e9e667cbd0fb804721ecbfc0cb4d0dda8a165437b3919
-SIZE (dna_features_viewer-3.1.3.tar.gz) = 40331
+TIMESTAMP = 1787345168
+SHA256 (dna_features_viewer-3.1.5.tar.gz) = 4740b018f7c45427054cb1403ff8b11209bcbe4ca9d5b77f28f14ed5ecb144c4
+SIZE (dna_features_viewer-3.1.5.tar.gz) = 30600
diff --git a/biology/py-dna-features-viewer/files/patch-pyproject.toml b/biology/py-dna-features-viewer/files/patch-pyproject.toml
new file mode 100644
index 000000000000..a3d813ee1d55
--- /dev/null
+++ b/biology/py-dna-features-viewer/files/patch-pyproject.toml
@@ -0,0 +1,12 @@
+--- pyproject.toml.orig	2026-08-21 20:46:49 UTC
++++ pyproject.toml
+@@ -1,7 +1,8 @@ version = "3.1.5"
+ [project]
+ name = "dna_features_viewer"
+ version = "3.1.5"
+-license = "MIT"
++# This causes a conflict, license cannot be given as both file and text
++# license = "MIT"
+ authors = [{ name = "Zulko" }]
+ description = "Plot features from DNA sequences (e.g. Genbank) with Python"
+ readme = "pypi-readme.rst"